| Gene Symbol | rl |
|---|---|
| Entrez Gene | 3354888 |
| Alt Symbol | 12559, BcDNA:RE08694, CG12559, CG18732, CT34260, CT39192, D-ERK, DERK, DERK-A, DmERK-A, DmERKA, DmErk, DmMAPK, Dmel\CG12559, DpERK, DpErk, Dsor2, E(sina)7, EK2-1, ERK, ERK-A, ERKA, ERKa, EY2-2, Erk, Erk/Map kinase, Erk1, ErkA, GroupII, MAP-k, MAPK, MapK, |
| Species | Drosophila |
| Gene Type | protein-coding |
| Description | rolled |
| Other Description | CG12559-PA|CG12559-PC|CG12559-PD|CG12559-PE|CG12559-PG|CG12559-PH|CG12559-PI|Diphospho-ERK|ERK|ERK/rolled|Erk MAP kinase|Extracellular-regulated kinase A|Extracellular-signal-related kinase A|MAP kinase|MAP-kinase|drosophila ERK|enhancer of seven in absentia 7|extracellular signal-regulated kinase|extracellular signal-regulated kinase A|mitogen activated protein kinase|mitogen-activated protein kinase|phospho-ERK|rl-PA|rl-PC|rl-PD|rl-PE|rl-PG|rl-PH|rl-PI|roll|sevenmaker |
| Swissprots | P40417 Q9W5M2 A8Y4W1 A0A021WW06 Q7PL59 Q9W5M3 A8Y4W2 |
| Accessions | AAB22532 EAA46310 EAA46311 EAA46312 EDP28106 EDP28107 EDP28108 EYR77323 P40417 AY070996 AAL48618 BT120325 ADC54216 M95124 AAA28677 NM_001015121 NP_001015121 NM_001015122 NP_001015122 NM_001015123 NP_001015123 NM_001110878 NP_001104348 NM_001110879 NP_001104349 NM_001110880 NP_001104350 NM_001300706 NP_001287635 |
| Function | Required downstream of Raf in the sevenless (sev), torso (tor), and Drosophila EGF receptor homolog (DER) signal transduction pathways. Required for embryonic epithelial tissue repair. {ECO:0000269|PubMed:22140578, ECO:0000269|PubMed:8157002}. |
| Subcellular Location | Cytoplasm {ECO:0000269|PubMed:1378625}. Nucleus {ECO:0000269|PubMed:1378625}. |
| Tissue Specificity | In third instar larvae, expressed in eye imaginal disks. In adults, expressed in head and body. {ECO:0000269|PubMed:1378625}. |
| Top Pathways | TGF-beta signaling pathway, mTOR signaling pathway, Dorso-ventral axis formation, MAPK signaling pathway - fly |
rolled (dN-19) - sc-15711 from Santa Cruz Biotechnology
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rl Antibody (OAAD00168) - OAAD00168 from Aviva Systems Biology
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Anti-Ephrin (N-terminal) polyclonal antibody - DPABH-00262 from Creative Diagnostics
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