INPP5K

Gene Symbol INPP5K
Entrez Gene 51763
Alt Symbol PPS, SKIP
Species Human
Gene Type protein-coding
Description inositol polyphosphate-5-phosphatase K
Other Description inositol polyphosphate 5-phosphatase K|skeletal muscle and kidney-enriched inositol phosphatase
Swissprots Q9P2R5 Q9NPJ5 B2R750 Q15733 D3DTH8 Q9BT40 B2R6I2
Accessions BAA92342 EAW90614 EAW90615 EAW90616 EAW90617 EAW90618 Q9BT40 AB036829 BAA92340 AB036830 BAA92341 AK297955 BAH12695 AK303907 BAH14079 AK307293 AK312585 BAG35479 AK312844 BAG35697 BC004362 AAH04362 BG722885 BM510617 DQ892815 ABM83741 DQ896061 ABM87060 U45973 AAB03214 XM_005256683 XP_005256740 XM_005256685 XP_005256742 XM_005256686 XP_005256743 XM_011523934 XP_011522236 XM_011523935 XP_011522237 XM_011523936 XP_011522238 NM_001135642 NP_001129114 NM_016532 NP_057616 NM_130766 NP_570122
Function Inositol 5-phosphatase which acts on inositol 1,4,5- trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5- trisphosphate. May negatively regulate assembly of the actin cytoskeleton. {ECO:0000269|PubMed:10753883}.
Subcellular Location Endoplasmic reticulum {ECO:0000269|PubMed:12536145}. Note=Following stimulation with EGF, translocates to membrane ruffles.
Tissue Specificity Ubiquitously expressed with highest levels in skeletal muscle, heart and kidney. {ECO:0000269|PubMed:10753883}.
Top Pathways Insulin signaling pathway, Inositol phosphate metabolism, Phosphatidylinositol signaling system

SKIP (B-6) - sc-365362 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SKIP (B-6): sc-365362. Western blot analysis of SKIP expression in non-transfected: sc-110760 (A) and human SKIP transfected: sc-158962 (B) 293 whole cell lysates.

SKIP (C-19) - sc-12073 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Skip (C-19): sc-12073. Western blot analysis of SKIP expression in non-transfected 293T: sc-117752 (A), human SKIP transfected 293T: sc-159714 (B) and HeLa (C) whole cell lysates.

SKIP (D-15) - sc-12071 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SKIP (D-15): sc-12071. Immunoperoxidase staining of formalin fixed, paraffin-embedded human duodenum tissue showing cytoplasmic staining of glandular cells.

Anti-SKIP antibody - ab154575 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-SKIP antibody (ab154575) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

Anti-SKIP antibody - ab113441 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-SKIP antibody (ab113441) at 1/500 dilution + Human fetal heart lysate

Anti-SKIP antibody - ab67715 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-SKIP antibody (ab67715) at 1/500 dilutionLane 1 : SKIP transfected 293T cell lysateLane 2 : non transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-INPP5K / SKIP Antibody (aa23-72) - LS-C151426 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
INPP5K / SKIP antibody Western Blot of MCF7.

Anti-INPP5K / SKIP Antibody (aa244-293) - LS-C135932 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
INPP5K / SKIP antibody LS-C135932 Western blot of Fetal Liver lysate. Antibody concentration 1 ug/ml.

Anti-INPP5K / SKIP Antibody - LS-C308499 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-INPP5K / SKIP Antibody - LS-C308501 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-INPP5K / SKIP Antibody (aa183-430) IHC-plus™ - LS-B10239 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-INPP5K / SKIP antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10239 concentration 10 ug/ml.

SKIP Antibody - NBP2-20379 from Novus Biologicals

Host Rabbit
Clonality Polyclonal
Western Blot: SKIP Antibody [NBP2-20379] - Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE gel, diluted at 1:1000.

SKIP Antibody - NBP1-74128 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SKIP Antibody [NBP1-74128] - Human Fetal Liver Lysate, Antibody Titration: 1 ug/ml, and Gel concentration: 12%

SKIP Antibody - NBP1-87034 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SKIP Antibody [NBP1-87034] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

SKIP Antibody - H00051763-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: SKIP Antibody [H00051763-B01P] - Analysis of INPP5K expression in transfected 293T cell line by INPP5K polyclonal antibody. Lane 1: INPP5K transfected lysate(49.28 KDa). Lane 2: Non-transfected lysate.

SKIP Antibody (3B4) - H00051763-M09 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3B4
Western Blot: SKIP Antibody (3B4) [H00051763-M09] - Analysis of INPP5K expression in human kidney.

Anti-SKIP (221-235) antibody produced in rabbit - S8823 from Sigma-Aldrich

Prices $342.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-SKIP (221-235) (RB): <B>Cat. No. S8823</B>: Immunofluorescence of HUVEC cells using SKIP (221-235) (RB), <B>Cat. No. S8823</B> (red) at a 1:50 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used.<BR/>Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-SKIP (246-260) antibody produced in rabbit - S8948 from Sigma-Aldrich

Prices $322.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-SKIP (246-260): <B>Cat. No. S8948</B>: Immunofluorescence of HUVEC cells using SKIP (246-260) (RB),<B>Cat. No. S8948</B> (red) at a 1:100 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-SKIP antibody produced in mouse - SAB1407521 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SKIP: <B>Cat. No. SAB1407521</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~49.3 kDa using INPP5K transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-INPP5K antibody produced in rabbit - HPA031044 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-INPP5K: <B>Cat. No. HPA031044</B>: Immunohistochemical staining of human duodenum shows moderate cytoplasmic positivity in glandular cells.

Monoclonal Anti-SKIP antibody produced in mouse - SAB1403265 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3B4
<B>Immunoblotting</B><BR/>Monoclonal Anti-SKIP: <B>Cat. No. SAB1403265</B>: Antibody concentration: 1 μg/mL. Specific band of ~75.4 kDa using immunogen protein lysate.

INPP5K antibody - C-terminal region (ARP61152_P050) - ARP61152_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

INPP5K antibody - N-terminal region (ARP61153_P050) - ARP61153_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

INPP5K antibody - orb77985 from Biorbyt

Prices $425.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of fetal heart lysate using INPP5K antibody

SkiP antibody - orb74409 from Biorbyt

Prices $723.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of mouse skeletal muscle tissue lysate using SkiP antibody
Search more