Gene Symbol | SLC2A4 |
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Entrez Gene | 6517 |
Alt Symbol | GLUT4 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 2 (facilitated glucose transporter), member 4 |
Other Description | GLUT-4|glucose transporter type 4, insulin-responsive|insulin-responsive glucose transporter type 4|solute carrier family 2, facilitated glucose transporter member 4 |
Swissprots | Q05BQ3 P14672 Q14CX2 |
Accessions | AAA52569 CAA41399 EAW90226 EAW90227 P14672 AK300899 BAG62537 AK313372 BAG36171 AL521328 BC034387 AAH34387 BC069615 AAH69615 BC069621 AAH69621 BC113592 AAI13593 BC126164 AAI26165 BQ775137 CF594356 HQ258267 ADR83021 M20747 AAA59189 NM_001042 NP_001033 |
Function | Insulin-regulated facilitative glucose transporter. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endomembrane system {ECO:0000269|PubMed:8300557}; Multi-pass membrane protein {ECO:0000269|PubMed:8300557}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:8300557}. Note=Localizes primarily to the perinuclear region, undergoing continued recycling to the plasma membrane where it is rapidly reinternalized. The dileucine internalization motif is critical for intracellular sequestration. |
Tissue Specificity | Skeletal and cardiac muscles; brown and white fat. |
Top Pathways | Insulin signaling pathway, Adipocytokine signaling pathway, Type II diabetes mellitus, AMPK signaling pathway |
Human Glucose Transporter GLUT4 full length protein - ab159519 from Abcam
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Human Glucose Transporter GLUT4 peptide - ab34088 from Abcam
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Human Glucose Transporter GLUT4 protein fragment - ab114176 from Abcam
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Rat Glucose Transporter GLUT4 peptide - ab115831 from Abcam
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Rat Glucose Transporter GLUT4 peptide - ab41800 from Abcam
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SLC2A4 / GLUT-4 Antibody Blocking Peptide - LS-E16097 from LifeSpan Bioscience
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SLC2A4 / GLUT-4 Antibody Blocking Peptide - LS-E27403 from LifeSpan Bioscience
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Glut4 Blocking Peptide - NBP1-49533PEP from Novus Biologicals
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Recombinant Human Glut4 Protein - H00006517-P01 from Novus Biologicals
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Recombinant Human Glut4 Protein - H00006517-Q01 from Novus Biologicals
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SLC2A4-Antibody-Center-Blocking-Peptide - BP16319c from Abgent, a WuXi AppTec company
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GLUT4 blocking peptide - GTX88031-PEP from GeneTex
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GLUT4 Blocking Peptide - 33R-5310 from Fitzgerald
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GLUT4 Blocking Peptide - 33R-11017 from Fitzgerald
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GLUT4 Blocking peptide (Mouse) - 30R-AG010 from Fitzgerald
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Glucose Transporter Glut4 Peptide - AC21-2227-P from Abcore
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GLUT4 / SLC2A4 - H00006517-P01 from Acris Antibodies
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GLUT4 / SLC2A4 - H00006517-Q01-10 from Acris Antibodies
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GLUT4 / SLC2A4 - H00006517-Q01-25 from Acris Antibodies
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SLC2A4 Peptide - 42-800P from ProSci
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GLUT4 fusion protein - ag15390 from Proteintech Group
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GLUT4 fusion protein - ag16920 from Proteintech Group
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Recombinant Human SLC2A4, GST-tagged - SLC2A4-2746H from Creative Biomart
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Recombinant Glucose Transporter 4 (GLUT4) - RPC023Hu01 from Uscn Life Science Inc.
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Recombinant Glucose Transporter 4 (GLUT4) - RPC023Mu01 from Uscn Life Science Inc.
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