Gene Symbol | RARS |
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Entrez Gene | 5917 |
Alt Symbol | ArgRS, DALRD1, HLD9 |
Species | Human |
Gene Type | protein-coding |
Description | arginyl-tRNA synthetase |
Other Description | arginine tRNA ligase 1, cytoplasmic|arginine--tRNA ligase, cytoplasmic|arginyl-tRNA synthetase, cytoplasmic |
Swissprots | P54136 B2RBS9 Q9BWA1 Q53GY4 |
Accessions | EAW61507 P54136 AK222797 BAD96517 AK302161 BAG63528 AK314795 BAG37326 AU125370 BC000528 AAH00528 BC014619 AAH14619 BM984528 BT007394 AAP36058 CA439316 S80343 AAB35627 NM_002887 NP_002878 |
Function | Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1. {ECO:0000269|PubMed:17443684}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:16055448, ECO:0000269|PubMed:16430231}. |
Top Pathways | Aminoacyl-tRNA biosynthesis |
ArgRS CRISPR/Cas9 KO Plasmid (h) - sc-409431 from Santa Cruz Biotechnology
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ArgRS HDR Plasmid (h) - sc-409431-HDR from Santa Cruz Biotechnology
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ArgRS Double Nickase Plasmid (h) - sc-409431-NIC from Santa Cruz Biotechnology
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ArgRS Double Nickase Plasmid (h2) - sc-409431-NIC-2 from Santa Cruz Biotechnology
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ArgRS CRISPR Activation Plasmid (h) - sc-409431-ACT from Santa Cruz Biotechnology
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ArgRS CRISPR Activation Plasmid (h2) - sc-409431-ACT-2 from Santa Cruz Biotechnology
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ArgRS Lentiviral Activation Particles (h) - sc-409431-LAC from Santa Cruz Biotechnology
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ArgRS Lentiviral Activation Particles (h2) - sc-409431-LAC-2 from Santa Cruz Biotechnology
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ArgRS siRNA (h) - sc-72532 from Santa Cruz Biotechnology
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ArgRS shRNA Plasmid (h) - sc-72532-SH from Santa Cruz Biotechnology
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ArgRS shRNA (h) Lentiviral Particles - sc-72532-V from Santa Cruz Biotechnology
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Arginyl tRNA synthetase RNAi - H00005917-R01 from Novus Biologicals
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MISSION® esiRNA - EHU052931 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17967 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17967 from Sigma-Aldrich
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RARS siRNA (Human) - CRH4003 from Cohesion Biosciences
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RARS - MBS8224771 from MyBioSource
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shRNA set against Human RARS (NM_002887.3) - SHH389824 from Creative biogene
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Human RARS siRNA - orb264505 from Biorbyt
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RARS shRNA Plasmid (Human) - CHH4003 from Cohesion Biosciences
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RARS miRNA 3'UTR clone - MiUTR1H-08638 from Creative biogene
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