Dnah8

Gene Symbol Dnah8
Entrez Gene 13417
Alt Symbol ATPase, Dnahc8, Hst6.7b, P1-Loop
Species Mouse
Gene Type protein-coding
Description dynein, axonemal, heavy chain 8
Other Description axonemal beta dynein heavy chain 8|axonemal dynein heavy chain 8 Dnahc8|ciliary dynein heavy chain 8|dynein heavy chain 8, axonemal|dynein, axon, heavy chain 8
Swissprots Q3V0D2 Q91XP9 E9Q010 Q91XQ0 Q91XP8 Q99MH8 O08830 Q91V63 Q9QY72
Accessions AAK18309 Q91XQ0 AF117305 AAF20213 AF356520 AAK60621 AF356521 AAK60622 AF356522 AAK60623 AF356523 AAK60624 AF363577 AAK60632 AF526535 AF526536 AK038133 AK133238 BAE21572 AK161258 BAE36274 BC032888 Z83817 CAB06071 XM_006523588 XP_006523651 XM_006523590 XP_006523653 XM_006523591 XP_006523654 XM_006523592 XP_006523655 NM_013811 NP_038839
Function Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly. {ECO:0000269|PubMed:10602986, ECO:0000269|PubMed:12297094}.
Subcellular Location Isoform 2: Cell projection, cilium, flagellum. Cytoplasm. Note=Detected in sperm tail, with almost exclusive localization to the principal piece. Also detected in the cytoplasm of primary spermatocytes. Location determined using antibody against peptide common to isoform 1 and isoform 2.
Tissue Specificity Isoform 1 and/or isoform 2 are expressed in spermatocytes and mature sperm (at protein level). Testis- specific. Accumulates exclusively in mid to late spermatocytes. {ECO:0000269|PubMed:10602986, ECO:0000269|PubMed:12297094, ECO:0000269|PubMed:16054618}.
Top Pathways Huntington's disease

ATP1B1 antibody, Internal - GTX88074 from GeneTex

Prices $299.00
Sizes 100 μg
Host Goat
Clonality Polyclonal
Anti-ATP1B1 antibody, Internal used in Western blot. GTX88074

ATP7B antibody - 70R-31697 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

ATPase antibody - 70R-31339 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

ATPase antibody (Ser16) - 70R-31338 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DNAH8 antibody - STJ72340 from St John's Laboratory Ltd

Host Goat
Clonality Polyclonal

ATPase, Polyclonal Antibody - MBS839186 from MyBioSource

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

ATPase, Polyclonal Antibody - MBS839666 from MyBioSource

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

ATP2C1 antibody - GTX31834 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-ATP2C1 antibody used in Western blot. GTX31834

ATP2C2 antibody - GTX32009 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-ATP2C2 antibody used in Western blot. GTX32009

ATPase, Polyclonal Antibody - MBS2027286 from MyBioSource

Prices $105.00, $125.00, $170.00, $210.00, $315.00, $745.00
Sizes 10 µg, 20 µg, 50 µg, 100 µg, 200 µg, 1 mg
Host Rabbit
Clonality Polyclonal

ATPase, Polyclonal Antibody - MBS2026659 from MyBioSource

Prices $110.00, $130.00, $185.00, $230.00, $345.00, $825.00
Sizes 10 µg, 20 µg, 50 µg, 100 µg, 200 µg, 1 mg
Host Rabbit
Clonality Polyclonal
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