DUSP6

Gene Symbol DUSP6
Entrez Gene 1848
Alt Symbol HH19, MKP3, PYST1
Species Human
Gene Type protein-coding
Description dual specificity phosphatase 6
Other Description MAP kinase phosphatase 3|dual specificity protein phosphatase 6|dual specificity protein phosphatase PYST1|mitogen-activated protein kinase phosphatase 3|serine/threonine specific protein phosphatase
Swissprots Q9BSH6 Q53Y75 O75109 Q16828
Accessions BAA31968 CBX53900 EAW97422 EAW97423 EAW97424 Q16828 AB013382 BAA34369 AB013602 BAA31969 AB189400 BAD38886 AB451265 BAG70079 AB451393 BAG70207 AK091753 AK222882 BAD96602 AU135449 BC003143 AAH03143 BC003562 AAH03562 BC005047 AAH05047 BC037236 AAH37236 BF087219 BT006895 AAP35541 DA105027 DQ892490 ABM83416 DQ895701 ABM86627 X93920 CAA63813 NM_001946 NP_001937 NM_022652 NP_073143
Function Inactivates MAP kinases. Has a specificity for the ERK family.
Subcellular Location Cytoplasm.
Top Pathways MAPK signaling pathway, Transcriptional misregulation in cancer

DUSP6/MKP3 Antibody - 3058 from Cell Signaling Technology

Prices $239.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cells using DUSP6/MKP3 Antibody.

MKP-3 (C-20) - sc-8599 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MKP-3 (C-20): sc-8599. Western blot analysis of MKP-3 expression in non-transfected: sc-117752 (A) and human MKP-3 transfected: sc-114251 (B) 293T whole cell lysates.

MKP-3 (F-12) - sc-377070 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MKP-3 (F-12): sc-377070. Western blot analysis of MKP-3 expression in non-transfected: sc-117752 (A) and mouse MKP-3 transfected: sc-121681 (B) 293T whole cell lysates.

MKP-3 (G-11) - sc-137245 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MKP-3 (G-11): sc-137245. Western blot analysis of MKP-3 expression in non-transfected: sc-117752 (A) and human MKP-3 transfected: sc-114251 (B) 293T whole cell lysates.

MKP-3 (G-12) - sc-166041 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MKP-3 (G-12): sc-166041. Western blot analysis of MKP-3 expression in non-transfected: sc-117752 (A) and human MKP-3 transfected: sc-114251 (B) 293T whole cell lysates.

MKP-3 (G-4) - sc-137246 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MKP-3 (G-4): sc-137246. Western blot analysis of MKP-3 expression in non-transfected: sc-117752 (A) and human MKP-3 transfected: sc-114251 (B) 293T whole cell lysates.

MKP-3 (H-130) - sc-28902 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
MKP-3 (H-130): sc-28902. Western blot analysis of human recombinant MKP-3 fusion protein.

MKP-3 (N-18) - sc-8598 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MKP-3 (N-18): sc-8598. Immunoperoxidase staining of formalin fixed, paraffin-embedded human bronchus tissue showing cytoplasmic staining of respiratory epithelial cells.

Anti-DUSP6 antibody - ab54940 from Abcam

Prices $390.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
DUSP6a antibody (ab54940) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human pancreas.

Anti-DUSP6 antibody - ab166922 from Abcam

Prices $376.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
All lanes : Anti-DUSP6 antibody (ab166922) at 0.3 µg/mlLane 1 : Human heart lysate (in RIPA buffer)Lane 2 : Mouse heart lysate (in RIPA buffer)Lane 3 : Rat heart lysate (in RIPA buffer)Lysates/proteins at 35 µg per lane.developed using the ECL technique

Anti-DUSP6 antibody - ab196690 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis of HeLa cells labeling DUSP6 with ab196690 at 1/100 dilution, in the presence (right panel) or absence (left panel) of immunizing peptide.

Anti-DUSP6 antibody - ab182605 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-DUSP6 antibody (ab182605) at 1/450 dilutionLane 1 : Jurkat cell lysateLane 2 : Human fetal kidney tissue lysateLysates/proteins at 30 µg per lane.SecondaryGoat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution

Anti-DUSP6 antibody - ab19115 from Abcam

Prices $378.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal

Anti-DUSP6 antibody - ab96750 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-DUSP6 antibody (ab96750) at 1/1000 dilution + A549 whole cell lysate at 30 µg

Anti-DUSP6 antibody - ab96807 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-DUSP6 antibody (ab96807) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

Anti-DUSP6 antibody - ab119886 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-DUSP6 antibody (ab119886) at 1/1000 dilutionLane 1 : Human fetal skin lysateLane 2 : 293T cell lysate

Anti-DUSP6 antibody - ab171882 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-DUSP6 antibody (ab171882) at 1 µg/mlLane 1 : DUSP6 transfected 293T cell lysate. at 15 µlLane 2 : Non-transfected 293T cell lysate. at 15 µldeveloped using the ECL technique

Anti-DUSP6 antibody - ab54551 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DUSP6 antibody [EPR129Y] - ab76310 from Abcam

Prices $403.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR129Y
Immunohistochemistry (PFA perfusion fixed frozen sections) analysis of Mouse brain tissue sections labelling DUSP6 with ab76310 at 1/400 dilution for 14 hours at 4°C. A biotinylated polyclonal anti-rabbit IgG was used as the secondary antibody at 1/250 dilution.See Abreview

Anti-DUSP6 antibody [EPR129Y] (Alexa Fluor® 488) - ab200750 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR129Y
ab200750 staining DUSP6 in PC12 cells. The cells were fixed with 4% formaldehyde (10min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab200750 at 1/200 dilution (shown in green) and ab195889, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 594), at 2µg/ml (shown in red). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-DUSP6 antibody [EPR129Y] (Alexa Fluor® 647) - ab200751 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR129Y
ab200751 staining DUSP6 in PC12 cells. The cells were fixed with 4% formaldehyde (10min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab200751 at 1/100 dilution (shown in red) and ab195887, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 488), at 2µg/ml (shown in green). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-DUSP6 / MKP3 Antibody (clone 3G2) IHC-plus™ - LS-B4314 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 3G2
Anti-DUSP6 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4314 concentration 5 ug/ml.

Anti-DUSP6 / MKP3 Antibody (aa135-280) - LS-C36214 from LifeSpan Bioscience

Prices $475.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal

Anti-DUSP6 / MKP3 Antibody (N-Terminus) - LS-C47084 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MKP3 / DUSP6 Antibody (aa135-280) - LS-C65055 from LifeSpan Bioscience

Prices $635.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal
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