Gene Symbol | PLA2G4E |
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Entrez Gene | 123745 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | phospholipase A2, group IVE |
Other Description | cPLA2-epsilon|cytosolic phospholipase A2 epsilon |
Swissprots | Q3MJ16 Q6ZSC0 |
Accessions | Q3MJ16 AI224165 AK127558 BAC87034 BC101584 AAI01585 BC101612 AAI01613 BC143436 BX648482 XM_011521237 XP_011519539 XM_011521238 XP_011519540 XM_011521239 XP_011519541 NM_001080490 NM_001206670 NP_001193599 |
Function | Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position. {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytosol. Lysosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Translocates to lysosomal membranes in a calcium-dependent fashion. {ECO:0000250}. |
Top Pathways | Glutamatergic synapse, Choline metabolism in cancer, Oxytocin signaling pathway, VEGF signaling pathway, Inflammatory mediator regulation of TRP channels |
group IVE sPLA 2 CRISPR/Cas9 KO Plasmid (h) - sc-417296 from Santa Cruz Biotechnology
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group IVE sPLA 2 HDR Plasmid (h) - sc-417296-HDR from Santa Cruz Biotechnology
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group IVE sPLA 2 Double Nickase Plasmid (h) - sc-417296-NIC from Santa Cruz Biotechnology
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group IVE sPLA 2 Double Nickase Plasmid (h2) - sc-417296-NIC-2 from Santa Cruz Biotechnology
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group IVE sPLA 2 CRISPR Activation Plasmid (h) - sc-417296-ACT from Santa Cruz Biotechnology
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group IVE sPLA 2 CRISPR Activation Plasmid (h2) - sc-417296-ACT-2 from Santa Cruz Biotechnology
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group IVE sPLA 2 Lentiviral Activation Particles (h) - sc-417296-LAC from Santa Cruz Biotechnology
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group IVE sPLA 2 Lentiviral Activation Particles (h2) - sc-417296-LAC-2 from Santa Cruz Biotechnology
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group IVE sPLA 2 siRNA (h) - sc-90083 from Santa Cruz Biotechnology
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group IVE sPLA 2 shRNA Plasmid (h) - sc-90083-SH from Santa Cruz Biotechnology
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group IVE sPLA 2 shRNA (h) Lentiviral Particles - sc-90083-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN16898 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16898 from Sigma-Aldrich
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PLA2G4E siRNA (Human) - CRJ4739 from Cohesion Biosciences
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PLA2G4E shRNA Plasmid (Human) - CHJ4739 from Cohesion Biosciences
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