| Gene Symbol |
REV3L
|
| Entrez Gene |
5980
|
| Alt Symbol |
POLZ, REV3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
|
| Other Description |
DNA polymerase zeta catalytic subunit|Rev-3, yeast, homolog-like (polymerase, DNA, zeta)
|
| Swissprots |
O60673 O43214 Q5TC33
|
| Accessions |
AAT74627 BAH59594 BAH69088 BAH69089 BAH69090 EAW48292 EAW48293 EAW48294 O60673 AB209256 BAD92493 AF004713 AAF21598 AF035537 AAB88486 AF058701 AAC24357 AF071798 AAC24009 AF078695 AAC28460 AF157476 AAD40184 AF179428 AAG09402 AF179429 AAG09403 AF303220 AK310949 AL096744 CAB62529 AW450927 BC035823 AAH35823 BC172423 AAI72423 BE645210 BP340028 HX785974 XM_006715543 XP_006715606 XM_006715544 XP_006715607 XM_011536028 XP_011534330 XM_011536029 XP_011534331 XM_011536030 XP_011534332 XM_011536031 XP_011534333 XM_011536032 XP_011534334 XM_011536033 XP_011534335 XM_011536034 XP_011534336 XM_011536035 XP_011534337 XM_011536036 XP_011534338 XR_942545 XR_942546 NM_001286431 NP_001273360 NM_001286432 NP_001273361 NM_002912 NP_002903
|
| Function |
Interacts with MAD2L2 to form the error prone DNA polymerase zeta involved in translesion DNA synthesis.
|
| Subcellular Location |
Nucleus {ECO:0000305}.
|
| Tissue Specificity |
Ubiquitously expressed.
|
| Top Pathways |
Fanconi anemia pathway
|