| Gene Symbol | LAMA4 |
|---|---|
| Entrez Gene | 3910 |
| Alt Symbol | CMD1JJ, LAMA3, LAMA4*-1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | laminin, alpha 4 |
| Other Description | laminin alpha 4 chain|laminin subunit alpha-4 |
| Swissprots | Q5SZG8 Q4LE44 Q9UJN9 Q9UE18 Q9BTB8 Q15335 Q14731 Q14735 Q16363 |
| Accessions | CAA74636 EAW48266 EAW48267 EAW48268 EAW48269 EAW48270 Q16363 AB210027 BAE06109 AJ710266 AK027151 AK304401 BAH14174 BC004241 AAH04241 BC026237 AAH26237 BC066552 AAH66552 BM014298 BM662226 BP234809 BT006690 AAP35336 BX648467 CR407622 CAG28550 DB271101 JF432726 ADZ15943 S78569 AAB34635 U77706 AAB36540 X70904 CAA50261 X76939 CAA54258 X91171 CAA62596 XM_005266983 XP_005267040 XM_005266984 XP_005267041 XM_011535821 XP_011534123 NM_001105206 NP_001098676 NM_001105207 NP_001098677 NM_001105208 NP_001098678 NM_001105209 NP_001098679 NM_002290 NP_002281 |
| Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. |
| Subcellular Location | Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component. |
| Tissue Specificity | In adult, strong expression in heart, lung, ovary small and large intestines, placenta, liver; weak or no expression in skeletal muscle, kidney, pancreas, testis, prostate, brain. High expression in fetal lung and kidney. Expression in fetal and newborn tissues is observed in certain mesenchymal cells in tissues such as smooth muscle and dermis. |
| Top Pathways | Focal adhesion, ECM-receptor interaction, Small cell lung cancer, Amoebiasis, Toxoplasmosis |