BAAT

Gene Symbol	BAAT
Entrez Gene	570
Alt Symbol	BACAT, BAT
Species	Human
Gene Type	protein-coding
Description	bile acid CoA:amino acid N-acyltransferase
Other Description	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)|bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase)|bile acid-CoA:amino acid N-acyltransferase|long-chain fatty-acyl-CoA hydrolase
Swissprots	Q14032 Q96L31 Q3B7W9
Accessions	EAW58943 EAW58944 EAW58945 EAW58946 Q14032 AK315347 BC009567 AAH09567 BC039200 BC107424 AAI07425 BG565737 CB154234 CR541918 CAG46716 DQ891910 ABM82836 DQ895095 ABM86021 H62757 L34081 AAC37550 NM_001127610 NP_001121082 NM_001701 NP_001692
Function	Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester, either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids, or both. The conjugation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-soluble vitamin absorption. In turn, bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very lo
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:12810727}.
Tissue Specificity	Expressed in liver, gallbladder mucosa and pancreas. {ECO:0000269|PubMed:12810727, ECO:0000269|PubMed:2037576}.
Top Pathways	Primary bile acid biosynthesis, Peroxisome, Bile secretion, Taurine and hypotaurine metabolism, Biosynthesis of unsaturated fatty acids

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

BAAT-Over-expression-Lysate - LY12191a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

BAAT overexpression lysate - LY419801 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

BAAT overexpression lysate - LY426822 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

BAAT 293 Cell Lysate - 409276 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

BAAT Overexpression Lysate (Native) - NBL1-07895 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

BAAT Over-expression Lysate Product - GWB-3E8587 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

BAAT Overexpression Lysate (Native) - NBP2-09453 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Panoply™ Human BAAT Knockdown Stable Cell Line - CSC-DC001289 from Creative biogene Category Cell Line Species Human

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