| Gene Symbol |
KRR1
|
| Entrez Gene |
11103
|
| Alt Symbol |
HRB2, RIP-1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
KRR1, small subunit (SSU) processome component, homolog (yeast)
|
| Other Description |
HIV-1 Rev binding protein 2|HIV-1 Rev-binding protein 2|KRR-R motif-containing protein 1|KRR1 small subunit processome component homolog|Rev interacting protein|rev-interacting protein 1
|
| Swissprots |
A0JLP0 A0FIK6 Q8NEA8 B2R989 Q96AT5 Q8TC37 Q13601 E7EUQ0
|
| Accessions |
EAW97309 Q13601 AK022133 AK297602 BAG59987 AK313687 BAG36436 BC005225 AAH05225 BC014034 BC016778 AAH16778 BC026107 AAH26107 BC033887 AAH33887 BM839950 DQ893552 ABM84478 DQ893553 ABM84479 DQ893554 ABM84480 DQ896515 ABM87514 EF010919 ABJ97679 U55766 AAB00557 NM_007043 NP_008974
|
| Function |
Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm. Nucleus, nucleolus. Note=Translocates from cytoplasm to nucleus after exposure to HIV- 1 virus or HIV-1 protein VPR or induction by hydrocortisone and dexamethasone in the absence of HIV-1 protein VPR.
|
![Western Blot: KRR1 Overexpression Lysate (Adult Normal) [NBL1-12379] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for KRR1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2049_KRR1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-12379-img0002.jpg)