Gene Symbol | ARX |
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Entrez Gene | 170302 |
Alt Symbol | CT121, EIEE1, ISSX, MRX29, MRX32, MRX33, MRX36, MRX38, MRX43, MRX54, MRX76, MRX87, MRXS1, PRTS |
Species | Human |
Gene Type | protein-coding |
Description | aristaless related homeobox |
Other Description | aristaless-related homeobox, X-linked|cancer/testis antigen 121|homeobox protein ARX |
Swissprots | Q96QS3 |
Accessions | EAW99031 EAW99032 Q96QS3 AA484051 AY038071 AAK93901 BC169333 BC169334 BF196892 BQ100952 BQ269551 CA775911 NM_139058 NP_620689 |
Function | Transcription factor required for normal brain development. May be important for maintenance of specific neuronal subtypes in the cerebral cortex and axonal guidance in the floor plate. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00138}. |
Tissue Specificity | Expressed predominantly in fetal and adult brain and skeletal muscle. Expression is specific to the telencephalon and ventral thalamus. There is an absence of expression in the cerebellum throughout development and also in adult. {ECO:0000269|PubMed:11889467, ECO:0000269|PubMed:11971879, ECO:0000269|PubMed:12359145}. |
ARX CRISPR/Cas9 KO Plasmid (h) - sc-402055 from Santa Cruz Biotechnology
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ARX HDR Plasmid (h) - sc-402055-HDR from Santa Cruz Biotechnology
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ARX Double Nickase Plasmid (h) - sc-402055-NIC from Santa Cruz Biotechnology
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ARX Double Nickase Plasmid (h2) - sc-402055-NIC-2 from Santa Cruz Biotechnology
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ARX CRISPR Activation Plasmid (h) - sc-402055-ACT from Santa Cruz Biotechnology
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ARX CRISPR Activation Plasmid (h2) - sc-402055-ACT-2 from Santa Cruz Biotechnology
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ARX Lentiviral Activation Particles (h) - sc-402055-LAC from Santa Cruz Biotechnology
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ARX Lentiviral Activation Particles (h2) - sc-402055-LAC-2 from Santa Cruz Biotechnology
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ARX siRNA (h) - sc-60204 from Santa Cruz Biotechnology
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ARX shRNA Plasmid (h) - sc-60204-SH from Santa Cruz Biotechnology
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ARX shRNA (h) Lentiviral Particles - sc-60204-V from Santa Cruz Biotechnology
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ARX RNAi - H00170302-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN3556 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3556 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04503 from Sigma-Aldrich
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ARX siRNA (Human) - CRJ6102 from Cohesion Biosciences
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ARX - MBS8212648 from MyBioSource
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shRNA set against Human Arx (NM_139058.2) - SHH241026 from Creative biogene
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shRNA set against Human ARX(NM_139058.2) - SHG075653 from Creative biogene
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ARX shRNA Plasmid (Human) - CHJ6102 from Cohesion Biosciences
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ARX miRNA 3'UTR clone - MiUTR1H-00616 from Creative biogene
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