Gene Symbol | Lig1 |
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Entrez Gene | 16881 |
Alt Symbol | AL033288, LigI |
Species | Mouse |
Gene Type | protein-coding |
Description | ligase I, DNA, ATP-dependent |
Other Description | DNA ligase 1|DNA ligase I|polydeoxyribonucleotide synthase [ATP] 1 |
Swissprots | P37913 |
Accessions | EDL38060 EDL38061 EDL38062 P37913 AK053906 BAC35585 AK153993 BAE32302 AK160208 AK161793 BAE36577 AK168643 AK178381 BC028287 AAH28287 BC138541 AAI38542 BC138542 AAI38543 BE996000 BY099263 U04674 AAA70403 U19604 AAB60500 NM_001083188 NP_001076657 NM_001199310 NP_001186239 NM_010715 NP_034845 |
Function | DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. |
Subcellular Location | Nucleus. |
Top Pathways | DNA replication, Mismatch repair, Base excision repair, Nucleotide excision repair |
DNA Ligase I CRISPR/Cas9 KO Plasmid (m) - sc-421434 from Santa Cruz Biotechnology
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DNA Ligase I HDR Plasmid (m) - sc-421434-HDR from Santa Cruz Biotechnology
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DNA Ligase I Double Nickase Plasmid (m) - sc-421434-NIC from Santa Cruz Biotechnology
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DNA Ligase I Double Nickase Plasmid (m2) - sc-421434-NIC-2 from Santa Cruz Biotechnology
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DNA Ligase I CRISPR Activation Plasmid (m) - sc-421434-ACT from Santa Cruz Biotechnology
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DNA Ligase I CRISPR Activation Plasmid (m2) - sc-421434-ACT-2 from Santa Cruz Biotechnology
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DNA Ligase I Lentiviral Activation Particles (m) - sc-421434-LAC from Santa Cruz Biotechnology
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DNA Ligase I Lentiviral Activation Particles (m2) - sc-421434-LAC-2 from Santa Cruz Biotechnology
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DNA Ligase I siRNA (m) - sc-35199 from Santa Cruz Biotechnology
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DNA Ligase I shRNA Plasmid (m) - sc-35199-SH from Santa Cruz Biotechnology
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DNA Ligase I shRNA (m) Lentiviral Particles - sc-35199-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU072751 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN34770 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND34770 from Sigma-Aldrich
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LIG1 siRNA (Mouse) - CRM2349 from Cohesion Biosciences
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shRNA set against Mouse LIG1 (NM_010715.2) - SHH330231 from Creative biogene
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shRNA set against Mouse Lig1(NM_001083188.1) - SHH149177 from Creative biogene
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shRNA set against Mouse Lig1(NM_010715.2) - SHH149231 from Creative biogene
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Mouse LIG1 siRNA - orb281825 from Biorbyt
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LIG1 shRNA Plasmid (Mouse) - CHM2349 from Cohesion Biosciences
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LIG1 miRNA 3'UTR clone - MiUTR1M-06641 from Creative biogene
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LIG1 miRNA 3'UTR clone - MiUTR1M-06642 from Creative biogene
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