Gene Symbol | Piga |
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Entrez Gene | 18700 |
Alt Symbol | AI194334, Pig-a |
Species | Mouse |
Gene Type | protein-coding |
Description | phosphatidylinositol glycan anchor biosynthesis, class A |
Other Description | N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein|glcNAc-PI synthesis protein|phosphatidylinositol glycan, class A|phosphatidylinositol-glycan biosynthesis class A protein|phosphatidylinositolglycan class A |
Swissprots | Q6LD71 Q8CCQ6 Q64323 |
Accessions | BAA06663 EDL40754 EDL40755 EDL40756 Q64323 AK014488 AK032283 BAC27792 AK039802 AK161026 BAE36154 AK171453 BAE42462 BB707289 BB771632 BC035538 BC051166 AAH51166 BC058767 AAH58767 BC138755 AAI38756 BC138758 AAI38759 BY270710 D26047 BAA05047 S78188 AAP32009 XM_006528758 XP_006528821 XM_011247793 XP_011246095 NM_011081 NP_035211 |
Function | Necessary for the synthesis of N-acetylglucosaminyl- phosphatidylinositol, the very early intermediate in GPI-anchor biosynthesis. |
Subcellular Location | Endoplasmic reticulum membrane; Single-pass membrane protein. |
Top Pathways | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis |
PIG-A CRISPR/Cas9 KO Plasmid (m) - sc-422226 from Santa Cruz Biotechnology
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PIG-A HDR Plasmid (m) - sc-422226-HDR from Santa Cruz Biotechnology
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PIG-A Double Nickase Plasmid (m) - sc-422226-NIC from Santa Cruz Biotechnology
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PIG-A Double Nickase Plasmid (m2) - sc-422226-NIC-2 from Santa Cruz Biotechnology
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PIG-A CRISPR Activation Plasmid (m) - sc-422226-ACT from Santa Cruz Biotechnology
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PIG-A CRISPR Activation Plasmid (m2) - sc-422226-ACT-2 from Santa Cruz Biotechnology
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PIG-A Lentiviral Activation Particles (m) - sc-422226-LAC from Santa Cruz Biotechnology
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PIG-A Lentiviral Activation Particles (m2) - sc-422226-LAC-2 from Santa Cruz Biotechnology
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PIG-A siRNA (m) - sc-61350 from Santa Cruz Biotechnology
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PIG-A shRNA Plasmid (m) - sc-61350-SH from Santa Cruz Biotechnology
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PIG-A shRNA (m) Lentiviral Particles - sc-61350-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU010871 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN38699 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND38699 from Sigma-Aldrich
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PIGA siRNA (Mouse) - CRM3055 from Cohesion Biosciences
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shRNA set against Mouse PIGA (NM_011081.2) - SHH375356 from Creative biogene
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shRNA set against Mouse Piga(NM_011081.2) - SHR113640 from Creative biogene
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Mouse PIGA siRNA - orb282531 from Biorbyt
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PIGA shRNA Plasmid (Mouse) - CHM3055 from Cohesion Biosciences
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PIGA miRNA 3'UTR clone - MiUTR1M-09191 from Creative biogene
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