| Gene Symbol |
HACL1
|
| Entrez Gene |
26061
|
| Alt Symbol |
2-HPCL, HPCL, HPCL2, PHYH2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
2-hydroxyacyl-CoA lyase 1
|
| Other Description |
1600020H07Rik|2-hydroxyphytanol-CoA lyase|2-hydroxyphytanoyl-CoA lyase|phytanoyl-CoA 2-hydroxylase 2|phytanoyl-CoA hydroxylase 2
|
| Swissprots |
B4DXI5 E9PEN4 Q9P0A2 B4DWI1 Q9UJ83 Q9BV42
|
| Accessions |
EAW64251 EAW64252 EAW64253 Q9UJ83 AA643224 AF161397 AAF28957 AJ131753 CAB60200 AK056977 BAG51836 AK301546 BAG63043 AK301990 BAG63397 AK302086 BAG63473 BC001627 AAH01627 BC007440 AAH07440 DA609383 DB049608 DB241165 DQ895558 ABM86484 EU176367 ABW03818 NM_001284413 NP_001271342 NM_001284415 NP_001271344 NM_001284416 NP_001271345 NM_012260 NP_036392 NR_104315
|
| Function |
Catalyzes a carbon-carbon cleavage reaction; cleaves a 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde.
|
| Subcellular Location |
Peroxisome.
|
| Tissue Specificity |
Expressed in high levels in liver, also expressed in kidney, heart and skeletal muscle. {ECO:0000269|PubMed:10468558}.
|
| Top Pathways |
Peroxisome
|