| Gene Symbol |
DET2
|
| Entrez Gene |
818383
|
| Alt Symbol |
ATDET2, DE-ETIOLATED 2, DWARF 6, DWF6, STEROID REDUCTASE DET2, T8P21.4, T8P21_4
|
| Species |
Arabidopsis thaliana
|
| Gene Type |
protein-coding
|
| Description |
probable steroid reductase DET2
|
| Other Description |
-
|
| Swissprots |
Q9SH83 Q38944
|
| Accessions |
AAD32767 AEC09484 Q38944 AY045926 AAK76600 AY079337 AAL85068 NM_129361 NP_181340
|
| Function |
Involved in a reduction step in the biosynthesis of the plant steroid, brassinolide; acts at the second step in brassinolide biosynthesis in the 5alpha-reduction of (24R)- 24- methylcholest-4-en-3-one, which is further modified to form campestanol. Can use progesterone, testosterone, androstenedione and campestenone as substrate. {ECO:0000269|PubMed:10398719, ECO:0000269|PubMed:11867704, ECO:0000269|PubMed:15993049, ECO:0000269|PubMed:8602526, ECO:0000269|PubMed:9108014, ECO:0000269|PubMed:9401120}.
|
| Subcellular Location |
Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Top Pathways |
Brassinosteroid biosynthesis
|