| Gene Symbol | DET2 |
|---|---|
| Entrez Gene | 818383 |
| Alt Symbol | ATDET2, DE-ETIOLATED 2, DWARF 6, DWF6, STEROID REDUCTASE DET2, T8P21.4, T8P21_4 |
| Species | Arabidopsis thaliana |
| Gene Type | protein-coding |
| Description | probable steroid reductase DET2 |
| Other Description | - |
| Swissprots | Q9SH83 Q38944 |
| Accessions | AAD32767 AEC09484 Q38944 AY045926 AAK76600 AY079337 AAL85068 NM_129361 NP_181340 |
| Function | Involved in a reduction step in the biosynthesis of the plant steroid, brassinolide; acts at the second step in brassinolide biosynthesis in the 5alpha-reduction of (24R)- 24- methylcholest-4-en-3-one, which is further modified to form campestanol. Can use progesterone, testosterone, androstenedione and campestenone as substrate. {ECO:0000269|PubMed:10398719, ECO:0000269|PubMed:11867704, ECO:0000269|PubMed:15993049, ECO:0000269|PubMed:8602526, ECO:0000269|PubMed:9108014, ECO:0000269|PubMed:9401120}. |
| Subcellular Location | Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Top Pathways | Brassinosteroid biosynthesis |