SENP2

Gene Symbol SENP2
Entrez Gene 59343
Alt Symbol AXAM2, SMT3IP2
Species Human
Gene Type protein-coding
Description SUMO1/sentrin/SMT3 specific peptidase 2
Other Description SMT3-specific isopeptidase 2|SUMO1/sentrin/SMT3 specific protease 2|sentrin-specific protease 2|sentrin/SUMO-specific protease SENP2
Swissprots Q96SR2 Q8IW97 Q9HC62 B4DQ42 Q9P2L5
Accessions EAW78214 EAW78215 EAW78216 EAW78217 Q9HC62 AF151697 AAG15309 AK027599 BAB55222 AK074357 AK296744 BAG59328 AK296772 BAG59351 AK298628 BAG60804 AK304402 BAG65236 AL834380 CAD39043 BC018020 BC040609 AAH40609 XM_005247690 XP_005247747 XM_005247691 XP_005247748 NM_021627 NP_067640
Function Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Deconjugates SUMO2 from MTA1. {ECO:0000269|PubMed:11896061, ECO:0000269|PubMed:12192048, ECO:0000269|PubMed:21965678}.
Subcellular Location Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Cytoplasm. Note=Shuttles between cytoplasm and nucleus.
Top Pathways Wnt signaling pathway, RNA transport

SENP2 CRISPR/Cas9 KO Plasmid (h) - sc-402148 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SENP2 HDR Plasmid (h) - sc-402148-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SENP2 Double Nickase Plasmid (h) - sc-402148-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SENP2 Double Nickase Plasmid (h2) - sc-402148-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SENP2 CRISPR Activation Plasmid (h) - sc-402148-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SENP2 CRISPR Activation Plasmid (h2) - sc-402148-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SENP2 Lentiviral Activation Particles (h) - sc-402148-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SENP2 Lentiviral Activation Particles (h2) - sc-402148-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SENP2 siRNA (h) - sc-44450 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SENP2 shRNA Plasmid (h) - sc-44450-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SENP2 shRNA (h) Lentiviral Particles - sc-44450-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU026371 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19086 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19086 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08912 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08912

SENP2 siRNA (Human) - CRJ1776 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SENP2 - MBS8201261 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SENP2 (NM_021627.2) - SHH404468 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SENP2(NM_021627.2) - SHR214662 from Creative biogene

Category siRNA
Species Reactivities Human

SENP2 shRNA Plasmid (Human) - CHJ1776 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SENP2 miRNA 3'UTR clone - MiUTR1H-09263 from Creative biogene

Species Reactivities Human
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