Gene Symbol | Scp2 |
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Entrez Gene | 20280 |
Alt Symbol | AA409774, AA409893, C76618, C79031, NSL-TP, SCP-2, SCP-X, SCPX, ns-LTP |
Species | Mouse |
Gene Type | protein-coding |
Description | sterol carrier protein 2, liver |
Other Description | SCP-chi|non-specific lipid-transfer protein|nonspecific lipid transfer protein|propanoyl-CoA C-acyltransferase|sterol carrier protein X |
Swissprots | P32020 A2APS2 Q9DBM7 A2APS3 |
Accessions | CAA62592 P32020 AK002425 BAB22092 AK004860 BB774576 BC018384 AAH18384 BC034613 AAH34613 CJ238474 DN176201 M62361 AAA40099 M91458 AAA40098 XM_011240477 XP_011238779 NM_011327 NP_035457 |
Function | Mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. May play a role in regulating steroidogenesis. |
Subcellular Location | Isoform SCPx: Peroxisome. Note=Interaction with PEX5 is essential for peroxisomal import. {ECO:0000250}. |
Tissue Specificity | Present at low levels in all tissues examined but expressed predominantly in the liver. |
Top Pathways | Primary bile acid biosynthesis, PPAR signaling pathway, Peroxisome |
SCP2 CRISPR/Cas9 KO Plasmid (m) - sc-422828 from Santa Cruz Biotechnology
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SCP2 HDR Plasmid (m) - sc-422828-HDR from Santa Cruz Biotechnology
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SCP2 Double Nickase Plasmid (m) - sc-422828-NIC from Santa Cruz Biotechnology
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SCP2 Double Nickase Plasmid (m2) - sc-422828-NIC-2 from Santa Cruz Biotechnology
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SCP2 CRISPR Activation Plasmid (m) - sc-422828-ACT from Santa Cruz Biotechnology
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SCP2 CRISPR Activation Plasmid (m2) - sc-422828-ACT-2 from Santa Cruz Biotechnology
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SCP2 Lentiviral Activation Particles (m) - sc-422828-LAC from Santa Cruz Biotechnology
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SCP2 Lentiviral Activation Particles (m2) - sc-422828-LAC-2 from Santa Cruz Biotechnology
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SCP2 siRNA (m) - sc-44637 from Santa Cruz Biotechnology
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SCP2 shRNA Plasmid (m) - sc-44637-SH from Santa Cruz Biotechnology
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SCP2 shRNA (m) Lentiviral Particles - sc-44637-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU073391 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN40796 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND40796 from Sigma-Aldrich
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SCP2 siRNA (Mouse) - CRM3616 from Cohesion Biosciences
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SCP2 - MBS8224508 from MyBioSource
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shRNA set against Mouse SCP2 (NM_011327.4) - SHH403008 from Creative biogene
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Mouse SCP2 siRNA - orb283092 from Biorbyt
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SCP2 shRNA Plasmid (Mouse) - CHM3616 from Cohesion Biosciences
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