Gene Symbol | FTL |
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Entrez Gene | 2512 |
Alt Symbol | LFTD, NBIA3 |
Species | Human |
Gene Type | protein-coding |
Description | ferritin, light polypeptide |
Other Description | ferritin L subunit|ferritin L-chain|ferritin light chain|ferritin light polypeptide-like 3 |
Swissprots | Q8WU07 Q86WI9 P02792 Q96AU9 Q6IBT7 Q96CU0 Q7Z2W1 B2R4B9 Q9BTZ8 |
Accessions | AAT66408 AAZ04399 AAZ04400 AGE97216 BAG16355 BAG16356 BAG16382 BAG16383 CAA27382 CAA27383 CAA27384 EAW52422 EAW52423 P02792 AF147331 AK026534 AK130191 AK130205 AK131048 AK131050 AK131053 AK307065 AK311773 BAG34716 AY207005 AAO52739 AY466472 AAS45711 BC002991 AAH02991 BC004245 AAH04245 BC008439 AAH08439 BC008441 BC013928 AAH13928 BC016346 AAH16346 BC016354 AAH16354 BC016715 AAH16715 BC018990 AAH18990 BC021670 AAH21670 BC058820 AAH58820 BC062708 AAH62708 BC067772 BX571748 CAE11873 CR456715 CAG32996 DQ892980 ABM83906 DQ896228 ABM87227 EU831925 ACE87366 EU832020 ACE86682 M10119 AAA35831 M11147 AAA52439 M12938 AAA52440 Y09188 CAA70387 NM_000146 NP_000137 |
Function | Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). {ECO:0000250}. |
Top Pathways | Mineral absorption |
ferritin light chain CRISPR/Cas9 KO Plasmid (h) - sc-400924 from Santa Cruz Biotechnology
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ferritin light chain HDR Plasmid (h) - sc-400924-HDR from Santa Cruz Biotechnology
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ferritin light chain Double Nickase Plasmid (h) - sc-400924-NIC from Santa Cruz Biotechnology
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ferritin light chain Double Nickase Plasmid (h2) - sc-400924-NIC-2 from Santa Cruz Biotechnology
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ferritin light chain CRISPR Activation Plasmid (h) - sc-400924-ACT from Santa Cruz Biotechnology
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ferritin light chain CRISPR Activation Plasmid (h2) - sc-400924-ACT-2 from Santa Cruz Biotechnology
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ferritin light chain Lentiviral Activation Particles (h) - sc-400924-LAC from Santa Cruz Biotechnology
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ferritin light chain Lentiviral Activation Particles (h2) - sc-400924-LAC-2 from Santa Cruz Biotechnology
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ferritin light chain siRNA (h) - sc-40577 from Santa Cruz Biotechnology
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ferritin light chain shRNA Plasmid (h) - sc-40577-SH from Santa Cruz Biotechnology
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ferritin light chain shRNA (h) Lentiviral Particles - sc-40577-V from Santa Cruz Biotechnology
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Ferritin Light Chain RNAi - H00002512-R01V from Novus Biologicals
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MISSION® esiRNA - EHU111441 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8979 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8979 from Sigma-Aldrich
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FTL siRNA (Human) - CRH1661 from Cohesion Biosciences
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Ferritin Light Chain RNAi - H00002512-R01 from Novus Biologicals
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FTL - MBS8207660 from MyBioSource
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ferritin light chain CRISPR/Cas9 KO Plasmid (h2) - sc-400924-KO-2 from Santa Cruz Biotechnology
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ferritin light chain HDR Plasmid (h2) - sc-400924-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human FTL(NM_000146.3) - SHH069563 from Creative biogene
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FTL shRNA Plasmid (Human) - CHH1661 from Cohesion Biosciences
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FTL miRNA 3'UTR clone - MiUTR1H-03867 from Creative biogene
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