Gene Symbol | HYAL2 |
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Entrez Gene | 8692 |
Alt Symbol | LUCA2 |
Species | Human |
Gene Type | protein-coding |
Description | hyaluronoglucosaminidase 2 |
Other Description | PH-20 homolog|PH20 homolog|hyal-2|hyaluronidase 2|hyaluronidase-2|hyaluronoglucosaminidase-2|lung carcinoma protein 2|lysosomal hyaluronidase |
Swissprots | Q12891 Q9BW29 B3KRZ2 O15177 |
Accessions | AAB67045 EAW65092 EAW65093 EAW65094 Q12891 AF070608 AAC28656 AJ000099 CAA03924 AJ844619 CAH59903 AJ844620 CAH59742 AK092449 BAG52554 AK127945 BAG54602 AK225635 AK310963 BC000692 AAH00692 BU626745 DB033601 DC358776 DC384113 DQ893838 ABM84764 EU176170 ABW03621 U09577 AAC62823 XM_005265524 XP_005265581 XM_005265525 XP_005265582 NM_003773 NP_003764 NM_033158 NP_149348 |
Function | Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product which is further hydrolyzed by sperm hyaluronidase to give small oligosaccharides. Displays very low levels of activity. Associates with and negatively regulates MST1R. {ECO:0000269|PubMed:11296287, ECO:0000269|PubMed:12676986, ECO:0000269|PubMed:9712871}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:11296287}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:11296287}. |
Tissue Specificity | Widely expressed. No expression detected in adult brain. {ECO:0000269|PubMed:9712871}. |
Top Pathways | Glycosaminoglycan degradation |
Human HYAL2 peptide - ab68606 from Abcam
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Human HYAL2 peptide - ab68607 from Abcam
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Human HYAL2 protein fragment - ab152907 from Abcam
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HYAL2 Antibody Blocking Peptide - LS-E446 from LifeSpan Bioscience
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HYAL2 Antibody Blocking Peptide - LS-E1714 from LifeSpan Bioscience
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HYAL2 Antibody Blocking Peptide - LS-E25820 from LifeSpan Bioscience
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Recombinant Human HYAL2 Protein - H00008692-Q01 from Novus Biologicals
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HYAL2-Antibody-C-term-Blocking-peptide - BP10730b from Abgent, a WuXi AppTec company
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HYAL2-Antibody-Center-Blocking-peptide - BP12491c from Abgent, a WuXi AppTec company
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Human HYAL2 protein - orb246152 from Biorbyt
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HYAL2 / Hyaluronidase-2 - H00008692-Q01-10 from Acris Antibodies
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HYAL2 / Hyaluronidase-2 - H00008692-Q01-25 from Acris Antibodies
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HYAL2 fusion protein - Ag7084 from Proteintech Group
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HYAL2 fusion protein - Ag7157 from Proteintech Group
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HYAL2 fusion protein - ag0582 from Proteintech Group
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Recombinant Human HYAL2, His-tagged - HYAL2-14019H from Creative Biomart
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Recombinant Hyaluronoglucosaminidase 2 (HYAL2) - RPE237Mu01 from Uscn Life Science Inc.
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Recombinant Human Hyaluronidase-2(HYAL2) - CSB-EP618635HU CSB-BP618635HU CSB-MP618635HU from Cusabio
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Recombinant Human Hyaluronidase-2(HYAL2) - CSB-YP618635HU from Cusabio
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HYAL2 Protein - abx163772 from Abbexa
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HYAL2 Recombinant Protein Antigen - NBP1-81283PEP from Novus Biologicals
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HYAL2 Antibody - SH-A12804 from Novatein Biosciences
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HYAL2 Peptide, Human - M34GP07365H from Creative Peptides
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HYAL2 Recombinant Protein (OPCA03000) - OPCA03000 from Aviva Systems Biology
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Recombinant Human Hyaluronidase-2(HYAL2) - RPC20266 from Biomatik
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