Gene Symbol | ERBB3 |
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Entrez Gene | 2065 |
Alt Symbol | ErbB-3, HER3, LCCS2, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3 |
Species | Human |
Gene Type | protein-coding |
Description | erb-b2 receptor tyrosine kinase 3 |
Other Description | human epidermal growth factor receptor 3|proto-oncogene-like protein c-ErbB-3|receptor tyrosine-protein kinase erbB-3|tyrosine kinase-type cell surface receptor HER3|v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 |
Swissprots | B4DIK7 B4DV32 A8K6L6 Q9BUD7 P21860 E9PDT8 |
Accessions | AAF86627 AAF86628 CCD32996 EAW96879 EAW96880 EAW96881 EAW96882 EAW96883 P21860 AA524528 AK124710 BAG54075 AK125028 BAG54127 AK291681 BAF84370 AK294719 BAG57868 AK295650 BAG58519 AK300909 BAG62544 AU100462 BC002706 AAH02706 BC041579 BC082992 AAH82992 BM837872 BT007226 AAP35890 BU674508 BX641868 DC344156 DC347955 M29366 AAA35790 M34309 AAA35979 S61953 AAB26935 U88357 AAC39857 U88358 AAC39858 U88359 AAC39859 U88360 AAC39860 NM_001005915 NP_001005915 NM_001982 NP_001973 |
Function | Binds and is activated by neuregulins and NTAK. May also be activated by CSPG5. {ECO:0000269|PubMed:15358134}. |
Subcellular Location | Isoform 1: Cell membrane; Single-pass type I membrane protein. |
Tissue Specificity | Epithelial tissues and brain. |
Top Pathways | ErbB signaling pathway, Calcium signaling pathway, Endocytosis, MicroRNAs in cancer, Proteoglycans in cancer |
Active human ErbB 3 protein fragment - ab155631 from Abcam
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Active human ErbB 3 protein fragment - ab155696 from Abcam
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ErbB 3 peptide (1330-1342) (Carboxyterminal end) - ab45806 from Abcam
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Human ErbB 3 full length protein - ab131831 from Abcam
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Human ErbB 3 protein fragment - ab196072 from Abcam
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Human ErbB 3 protein fragment - ab201905 from Abcam
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Human ErbB 3 protein fragment - ab73634 from Abcam
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ERBB3 / HER3 Antibody Blocking Peptide - LS-E25937 from LifeSpan Bioscience
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ERBB3 / HER3 Antibody Blocking Peptide - LS-E9126 from LifeSpan Bioscience
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ErbB3/Her3 Partial Recombinant Protein - H00002065-Q01 from Novus Biologicals
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ErbB3/Her3 Recombinant Protein - H00002065-P01 from Novus Biologicals
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ErbB3/Her3 Peptide - P2654 from Novus Biologicals
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ERBB3-Antibody-N-term-Blocking-peptide - BP7630a from Abgent, a WuXi AppTec company
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Her3 / ErbB3 blocking peptide - GTX89440-PEP from GeneTex
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Recombinant Human ErbB3 Fc Chimera, CF - 348-RB-050 from R&D Systems
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ErbB3 Protein (OPPA01566) - OPPA01566 from Aviva Systems Biology
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Human ErbB3 protein - orb138814 from Biorbyt
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Human ErbB3 protein - orb168493 from Biorbyt
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Human HER3 protein - orb232216 from Biorbyt
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Human ErbB3 protein (GST Tag) - orb138811 from Biorbyt
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Human ErbB3 His tag protein - orb83621 from Biorbyt
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Human ErbB3 Fc tag protein - orb82991 from Biorbyt
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ERBB3 Immunizing peptide - orb15317 from Biorbyt
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ERBB3 protein - 80R-4263 from Fitzgerald
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ErbB 3 Peptide - AC21-0766-P from Abcore
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