Gene Symbol | PRAP1 |
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Entrez Gene | 118471 |
Alt Symbol | PRO1195, UPA |
Species | Human |
Gene Type | protein-coding |
Description | proline-rich acidic protein 1 |
Other Description | epididymis tissue protein Li 178 |
Swissprots | Q5VWY4 Q8NCS2 B7ZL58 B7ZL57 E9KL31 Q7Z4X5 Q96NZ9 Q8IWR3 |
Accessions | EAW61336 Q96NZ9 AF123768 AAP97247 AF421885 AAL16670 AY158074 AAN87018 AY358908 AAQ89267 BC029447 AAH29447 BC061643 AAH61643 BC071872 AAH71872 BC093853 AAH93853 BC101743 AAI01744 BC143590 AAI43591 BC143591 AAI43592 BC143592 AAI43593 DQ884405 ABI63372 GU727628 ADU87630 HQ447527 ADQ32013 NM_001145201 NP_001138673 NM_145202 NP_660203 |
Function | May play an important role in maintaining normal growth homeostasis in epithelial cells. {ECO:0000269|PubMed:14583459}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:14583459}. |
Tissue Specificity | Abundantly expressed in the epithelial cells of the liver, kidney, gastrointestinal tract and cervix. Significantly down-regulated in hepatocellular carcinoma and right colon adenocarcinoma compared with the respective adjacent normal tissues. Expressed in epididymis (at protein level). {ECO:0000269|PubMed:14583459, ECO:0000269|PubMed:20736409}. |
PRAP1 CRISPR/Cas9 KO Plasmid (h) - sc-414124 from Santa Cruz Biotechnology
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PRAP1 HDR Plasmid (h) - sc-414124-HDR from Santa Cruz Biotechnology
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PRAP1 Double Nickase Plasmid (h) - sc-414124-NIC from Santa Cruz Biotechnology
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PRAP1 Double Nickase Plasmid (h2) - sc-414124-NIC-2 from Santa Cruz Biotechnology
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PRAP1 CRISPR Activation Plasmid (h) - sc-414124-ACT from Santa Cruz Biotechnology
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PRAP1 CRISPR Activation Plasmid (h2) - sc-414124-ACT-2 from Santa Cruz Biotechnology
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PRAP1 Lentiviral Activation Particles (h) - sc-414124-LAC from Santa Cruz Biotechnology
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PRAP1 Lentiviral Activation Particles (h2) - sc-414124-LAC-2 from Santa Cruz Biotechnology
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PRAP1 siRNA (h) - sc-90366 from Santa Cruz Biotechnology
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PRAP1 shRNA Plasmid (h) - sc-90366-SH from Santa Cruz Biotechnology
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PRAP1 shRNA (h) Lentiviral Particles - sc-90366-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU120361 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17359 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17359 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01308 from Sigma-Aldrich
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PRAP1 siRNA (Human) - CRJ4586 from Cohesion Biosciences
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shRNA set against Human PRAP1 (NM_145202.4) - SHH382048 from Creative biogene
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Human PRAP1 siRNA - orb275087 from Biorbyt
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PRAP1 shRNA Plasmid (Human) - CHJ4586 from Cohesion Biosciences
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PRAP1 miRNA 3'UTR clone - MiUTR3H-10798 from Creative biogene
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PRAP1 miRNA 3'UTR clone - MiUTR3H-10799 from Creative biogene
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