CRHR2

Gene Symbol	CRHR2
Entrez Gene	1395
Alt Symbol	CRF-RB, CRF2, CRFR2, HM-CRF
Species	Human
Gene Type	protein-coding
Description	corticotropin releasing hormone receptor 2
Other Description	CRF2 receptor, beta isoform|CRH receptor 2 variant B|CRH-R2|corticotropin-releasing factor receptor 2
Swissprots	Q4QRJ4 Q13324 B3SXS6 O43461 F8WA81 B3SXS8 Q99431 B3SXT0 B2R967 B3SXS7
Accessions	AAC71653 AAC71654 BAC05922 CAD69350 CAP40149 CAP40151 EAL24448 EAW93962 EAW93963 EAW93964 EAW93965 Q13324 AF011406 AAB94503 AF019381 AAB94562 AF361106 AF361107 AF361108 AK313661 BAG36414 AY449734 AAR18078 BC096830 AAH96830 CN367943 CN367944 DA808296 DB308619 EU012439 ABV59313 EU012440 ABV59314 EU012441 ABV59315 EU012442 ABV59316 EU012443 ABV59317 FJ200484 ACO54881 U34587 AAA91320 Y10151 CAA71235 Y10152 CAA71236 Y10153 XM_011515127 XP_011513429 XM_011515128 XP_011513430 XM_011515129 XP_011513431 NM_001202475 NP_001189404 NM_001202481 NP_001189410 NM_001202482 NP_001189411 NM_001202483 NP_001189412 NM_001883 NP_001874
Function	G-protein coupled receptor for CRH (corticotropin- releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:22689579}; Multi-pass membrane protein {ECO:0000269|PubMed:22689579}.
Top Pathways	Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Corticotropin Releasing Factor Receptor 2 full length protein - ab152298 from Abcam Category Protein Source Wheat germ Species Human

CRHR2 / CRF2 Receptor Antibody Blocking Peptide - LS-E990 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CRHR2 / CRF2 Receptor Antibody Blocking Peptide - LS-E911 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CRHR2 / CRF2 Receptor Antibody Blocking Peptide - LS-E28782 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CRHR2 / CRF2 Receptor Antibody Blocking Peptide - LS-E28781 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CRHR2 / CRF2 Receptor Antibody Blocking Peptide - LS-E29022 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CRHR2 / CRF2 Receptor Antibody Blocking Peptide - LS-E29025 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CRHR2 / CRF2 Receptor Antibody Blocking Peptide - LS-E28952 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CRHR2 / CRF2 Receptor Antibody Blocking Peptide - LS-E8458 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CRHR2 / CRF2 Receptor Antibody Blocking Peptide - LS-E8459 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CRHR2 / CRF2 Receptor Antibody Blocking Peptide - LS-E23372 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CRHR2/CRF2 Protein - H00001395-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

CRHR2/CRF2 Peptide - NLS3573PEP from Novus Biologicals Category Peptide Prices $369.00 Sizes 50 µg Species Human

Recombinant Human CRHR2/CRF2 Protein - H00001395-G01 from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Source Wheat Germ Species Human

CRFR2D-Antibody-Blocking-peptide - BP11312a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

CRFR2-Antibody-D35-Blocking-peptide - BP11442a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CRHR2-Antibody-Center-Blocking-Peptide - BP6787c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CRHR2-Antibody-N-term-Blocking-Peptide - BP6787a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CRHR2 Blocking Peptide - abx062468 from Abbexa Category Peptide Species Human, Mouse, Rat, Pig

CRHR2 - H00001395-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

CRHR2 - H00001395-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

Recombinant Corticotropin Releasing Hormone Receptor 2 (CRHR2) - RPD513Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Corticotropin Releasing Hormone Receptor 2 (CRHR2) - RPD513Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

ChemiSCREEN™ Membrane Preparation Recombinant Human CRF 2 Neuropeptide Receptor - HTS024M from EMD Millipore Prices $596.00 Sizes 200 units Species Human

CRHR2 Blocking Peptide - CBP1274 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Pig

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