PLG

Gene Symbol PLG
Entrez Gene 733660
Alt Symbol -
Species Pig
Gene Type protein-coding
Description plasminogen
Other Description -
Swissprots Q19AZ9 P06867
Accessions P06867 AK232298 AK232527 AK232883 AK346154 AK394190 DQ530369 ABF82358 XM_005659111 XP_005659168 NM_001044590 NP_001038055
Function Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells (By similarity). {ECO:0000250}.
Subcellular Location Secreted {ECO:0000250}. Note=Locates to the cell surface where it is proteolytically cleaved to produce the active plasmin. Interaction with HRG tethers it to the cell surface (By similarity). {ECO:0000250}.
Top Pathways Complement and coagulation cascades, Staphylococcus aureus infection, Influenza A, Neuroactive ligand-receptor interaction

Plasminogen, Polyclonal Antibody - MBS2026927 from MyBioSource

Prices $170.00, $340.00, $530.00
Sizes 20 µg, 100 µg, 200 µg
Host Rabbit
Clonality Polyclonal

Plasminogen - ARB-65095 from Nordic BioSite

Host Rabbit
Clone polyclonal
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