| Gene Symbol |
HIVEP2
|
| Entrez Gene |
3097
|
| Alt Symbol |
HIV-EP2, MBP-2, MIBP1, SHN2, ZAS2, ZNF40B
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
human immunodeficiency virus type I enhancer binding protein 2
|
| Other Description |
MHC binding protein-2|MHC-binding protein 2|Schnurri-2|c-myc intron binding protein 1|human immunodeficiency virus type I enhancer-binding protein 2|transcription factor HIVEP2
|
| Swissprots |
P31629 Q5THT5 Q9NS05 Q02646
|
| Accessions |
AAB88218 AAF81365 EAW47873 P31629 AA041301 AA465317 AK226163 AK296531 BAG59161 AW197846 BC032679 BC167801 AAI67801 CR936782 DA216380 DQ231041 ABB16331 M61744 AAA36202 X65644 CAA46596 NM_006734 NP_006725
|
| Function |
This protein specifically binds to the DNA sequence 5'- GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, somatostatin receptor II, and interferon- beta genes. It may act in T-cell activation.
|
| Subcellular Location |
Nucleus.
|
| Tissue Specificity |
Expressed in brain and skeletal muscle. {ECO:0000269|PubMed:10207097}.
|