Gene Symbol | BMP4 |
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Entrez Gene | 652 |
Alt Symbol | BMP2B, BMP2B1, MCOPS6, OFC11, ZYME |
Species | Human |
Gene Type | protein-coding |
Description | bone morphogenetic protein 4 |
Other Description | BMP-2B|BMP-4|bone morphogenetic protein 2B |
Swissprots | Q9UM80 P12644 |
Accessions | AAC72278 ACB21039 AIU47303 AIU47304 AIU47305 AIU47306 CAD57968 CBE74713 CCQ43131 EAW80628 EAW80629 EAW80630 EAW80631 P12644 BC020546 AAH20546 BQ083000 BU683974 BX161385 CAD61876 BX161438 CAD61909 D30751 BAA06410 EU176183 ABW03634 HQ447921 ADQ32405 KF250427 AGW21692 M22490 AAA51835 XM_005268015 XP_005268072 NM_001202 NP_001193 NM_130850 NP_570911 NM_130851 NP_570912 |
Function | Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix. |
Tissue Specificity | Expressed in the lung and lower levels seen in the kidney. Present also in normal and neoplastic prostate tissues, and prostate cancer cell lines. |
Top Pathways | Hedgehog signaling pathway, TGF-beta signaling pathway, Basal cell carcinoma, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells |
BMP4 (6B7) Mouse mAb - 4680 from Cell Signaling Technology
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BMP-4 (3H2.3) - sc-12721 from Santa Cruz Biotechnology
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BMP-4 (9H4) - sc-81000 from Santa Cruz Biotechnology
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BMP-4 (D-6) - sc-393329 from Santa Cruz Biotechnology
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BMP-4 (N-16) - sc-6896 from Santa Cruz Biotechnology
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BMP-4 (66119.11) - sc-73536 from Santa Cruz Biotechnology
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Anti-BMP4 antibody - ab31165 from Abcam
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Anti-BMP4 antibody - ab155033 from Abcam
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Anti-BMP4 antibody - ab38342 from Abcam
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Anti-BMP4 antibody [3H2] - ab81194 from Abcam
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Anti-BMP4 antibody [66119.11] - ab6296 from Abcam
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Anti-BMP4 antibody [EPR6211] - ab124715 from Abcam
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Anti-BMP4 antibody [EPR6211] (Alexa Fluor® 488) - ab200794 from Abcam
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Anti-BMP4 antibody [EPR6211] (Alexa Fluor® 568) - ab202527 from Abcam
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Anti-BMP4 antibody [EPR6211] (Alexa Fluor® 647) - ab200796 from Abcam
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Anti-BMP4 antibody [EPR6211] (HRP) - ab200795 from Abcam
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Anti-BMP4 antibody, prediluted - ab31166 from Abcam
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Anti-BMP4 antibody - C-terminal - ab135088 from Abcam
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Anti-BMP4 Antibody (clone 6B7) - LS-C114311 from LifeSpan Bioscience
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Anti-BMP4 Antibody (aa23-204, Biotin) - LS-C297130 from LifeSpan Bioscience
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Anti-BMP4 Antibody (aa209-392, Biotin) - LS-C297742 from LifeSpan Bioscience
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Anti-BMP4 Antibody (aa219-392) - LS-C293039 from LifeSpan Bioscience
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Anti-BMP4 Antibody (aa293-408) - LS-C293038 from LifeSpan Bioscience
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Anti-BMP4 Antibody (aa28-183, Biotin) - LS-C299089 from LifeSpan Bioscience
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Anti-BMP4 Antibody (aa219-392, Biotin) - LS-C299414 from LifeSpan Bioscience
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