Gene Symbol | HLA-DOB |
---|---|
Entrez Gene | 3112 |
Alt Symbol | DOB |
Species | Human |
Gene Type | protein-coding |
Description | major histocompatibility complex, class II, DO beta |
Other Description | HLA class II histocompatibility antigen, DO beta chain|MHC class II antigen DOB |
Swissprots | Q29746 Q6FHC2 Q29825 B0V0Y0 P13765 |
Accessions | AAA59717 AHW47923 AHW47940 AHW47957 AHW47974 CAA47028 CAA60789 EAX03638 EAX03639 EAX03640 EAX03641 P13765 AK301415 BAH13478 AK316197 BAH14568 AY645723 AAV97948 BC006097 AAH06097 BC020226 BM152694 BQ010608 CR541811 CAG46610 CR541832 CAG46631 M26040 AAA59718 X03066 CAA26870 NM_002120 NP_002111 |
Function | Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B-cells. Modifies peptide exchange activity of HLA-DM. |
Subcellular Location | Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=Complexes with HLA-DM molecule during intracellular transport and in endosomal/lysosomal compartments. Heterotetramerization is necessary to exit the ER. |
Top Pathways | Leishmaniasis, HTLV-I infection, Influenza A, Tuberculosis, Herpes simplex infection |
Human HLA DOB protein fragment - ab158655 from Abcam
|
||||||||||
Human HLA DOB protein fragment - ab180287 from Abcam
|
||||||||||
HLA-DOB Antibody Blocking Peptide - LS-E22532 from LifeSpan Bioscience
|
||||||||||
HLA DOB Partial Recombinant Protein - H00003112-Q01 from Novus Biologicals
|
||||||||||
HLA-DOB peptide - orb217393 from Biorbyt
|
||||||||||
HLA-DOB protein (His tag) - 80R-3816 from Fitzgerald
|
||||||||||
HLA-DOB Blocking Peptide - abx062724 from Abbexa
|
||||||||||
HLA class II DO beta / HLA-DOB (27-224, His-tag) - AR51503PU-N from Acris Antibodies
|
||||||||||
HLA class II DO beta / HLA-DOB (27-224, His-tag) - AR51503PU-S from Acris Antibodies
|
||||||||||
HLA class II DO beta / HLA-DOB - H00003112-Q01-10 from Acris Antibodies
|
||||||||||
HLA class II DO beta / HLA-DOB - H00003112-Q01-25 from Acris Antibodies
|
||||||||||
HLA-DOB, 27-224aa, Human, His tag, E.coli - 01-P2683 from ARP American Research Products
|
||||||||||
HLA-DOB fusion protein - ag2062 from Proteintech Group
|
||||||||||
Recombinant Human HLA-DOB, GST-tagged - HLA-DOB-13815H from Creative Biomart
|
||||||||||
Recombinant Human HLA-DOB, His-tagged - HLA-DOB-190H from Creative Biomart
|
||||||||||
HLA-DOB Blocking Peptide - CBP1530 from Cohesion Biosciences
|
||||||||||
HLA-DOB Peptide - BS5758P from Bioworld Technology
|
||||||||||
Recombinant Human HLA class II histocompatibility antigen, DO beta chain(HLA-DO - CSB-YP318411HU CSB-EP318411HU CSB-BP318411HU CSB-MP318411HU from Cusabio
|
||||||||||
HLA-DOB, 27-224aa, Human, His tag, E.coli (Denatured) - ATGP2683 from ATGen
|
||||||||||
HLA class II DO beta / HLA-DOB - TP302892 from Acris Antibodies
|
||||||||||
HLA DOB Protein - NBP1-87469PEP from Novus Biologicals
|
||||||||||
HLA-DOB Peptide, Human - M34GP07090H from Creative Peptides
|
||||||||||
HLA class II histocompatibility antigen, DO beta chain (232-240) - ta-346 from Creative Peptides
|
||||||||||
Human HLA-DOB protein - orb259921 from Biorbyt
|
||||||||||
Recombinant Human HLA DOB Protein - NBP2-51696 from Novus Biologicals
|