Gene Symbol | SLC9A2 |
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Entrez Gene | 6549 |
Alt Symbol | NHE2 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
Other Description | Na(+)/H(+) exchanger 2|sodium/hydrogen exchanger 2|solute carrier family 9 (sodium/hydrogen exchanger)|solute carrier family 9 (sodium/hydrogen exchanger), member 2|solute carrier family 9 member 2 |
Swissprots | B2RMS2 Q9UBY0 |
Accessions | AAF19248 AAK58694 EAX01788 EAX01789 Q9UBY0 AA843986 AF073299 AAD41635 AK129936 BC035787 BC136377 AAI36378 BC136378 AAI36379 S83549 AAB50820 NM_003048 NP_003039 |
Function | Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Seems to play an important role in colonic sodium absorption. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in skeletal muscle, colon and kidney. Lower levels in the testis, prostate, ovary, and small intestine. |
NHE-2 CRISPR/Cas9 KO Plasmid (h) - sc-404353 from Santa Cruz Biotechnology
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NHE-2 HDR Plasmid (h) - sc-404353-HDR from Santa Cruz Biotechnology
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NHE-2 Double Nickase Plasmid (h) - sc-404353-NIC from Santa Cruz Biotechnology
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NHE-2 Double Nickase Plasmid (h2) - sc-404353-NIC-2 from Santa Cruz Biotechnology
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NHE-2 CRISPR Activation Plasmid (h) - sc-404353-ACT from Santa Cruz Biotechnology
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NHE-2 CRISPR Activation Plasmid (h2) - sc-404353-ACT-2 from Santa Cruz Biotechnology
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NHE-2 Lentiviral Activation Particles (h) - sc-404353-LAC from Santa Cruz Biotechnology
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NHE-2 Lentiviral Activation Particles (h2) - sc-404353-LAC-2 from Santa Cruz Biotechnology
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NHE-2 siRNA (h) - sc-42652 from Santa Cruz Biotechnology
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NHE-2 shRNA Plasmid (h) - sc-42652-SH from Santa Cruz Biotechnology
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NHE-2 shRNA (h) Lentiviral Particles - sc-42652-V from Santa Cruz Biotechnology
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SLC9A2 RNAi - H00006549-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN19701 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19701 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11887 from Sigma-Aldrich
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SLC9A2 siRNA (Human) - CRH4441 from Cohesion Biosciences
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SLC9A2 - MBS8205513 from MyBioSource
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shRNA set against Human SLC9A2 (NM_003048.3) - SHH412284 from Creative biogene
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shRNA set against Human SLC9A2(NM_003048.3) - SHL012360 from Creative biogene
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SLC9A2 shRNA Plasmid (Human) - CHH4441 from Cohesion Biosciences
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SLC9A2 miRNA 3'UTR clone - MiUTR1H-09608 from Creative biogene
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