| Gene Symbol |
inaC
|
| Entrez Gene |
36897
|
| Alt Symbol |
CG6518, Dmel\CG6518, Dpkc2, INAC, InaC, PK-C, PKC, PKC 53E, PKCi, Pkc2, dPKC53E, dPKC53E(ey), ePKC, eye PKC, eye-PKC, pkc-2
|
| Species |
Drosophila
|
| Gene Type |
protein-coding
|
| Description |
inactivation no afterpotential C
|
| Other Description |
CG6518-PA|PKC-eye|Protein-kinase-2|eye-PKC|eye-protein-kinase C|eye-specific PKC|inaC-PA|protein kinase C|protein kinase-c2|protein-kinase-C
|
| Swissprots |
Q9V7V5 P13677
|
| Accessions |
AAF57934 P13677 BT004495 AAO42659 J04845 AAA28817 NM_057515 NP_476863
|
| Function |
This is a calcium-activated, phospholipid-dependent, serine- and threonine-specific enzyme. This isozyme is a negative regulator of the visual transduction cascade and has been shown to be required for photoreceptor cell inactivation and light adaptation. Negative regulation is dependent on interaction with scaffolding protein inaD. {ECO:0000269|PubMed:2720775}.
|
| Tissue Specificity |
Exclusively expressed in photoreceptor cells. {ECO:0000269|PubMed:2720775}.
|
| Top Pathways |
Wnt signaling pathway, Phototransduction - fly, mTOR signaling pathway, Phosphatidylinositol signaling system
|