Gene Symbol | SYNJ1 |
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Entrez Gene | 8867 |
Alt Symbol | INPP5G, PARK20 |
Species | Human |
Gene Type | protein-coding |
Description | synaptojanin 1 |
Other Description | inositol 5'-phosphatase (synaptojanin 1)|synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1|synaptic inositol-1,4,5-trisphosphate 5-phosphatase 1|synaptojanin-1|synaptojanin-1, polyphosphoinositide phosphatase |
Swissprots | O94984 Q4KMR1 O43426 O43425 |
Accessions | CAR81404 CBX84866 EAX09863 EAX09864 O43426 AB020717 BAA74933 AF009039 AAC51921 AF009040 AAC51922 AK295706 BAG58552 AK304044 BAG64955 AK307762 AL109818 BC019630 AAH19630 BC067231 BC098395 AAH98395 BC136603 AAI36604 BP350252 CA944966 DB071394 DQ421853 ABD77575 NM_001160302 NP_001153774 NM_001160306 NP_001153778 NM_003895 NP_003886 NM_203446 NP_982271 |
Function | Inositol 5-phosphatase which has a role in clathrin- mediated endocytosis. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Tissue Specificity | Concentrated at clathrin-coated endocytic intermediates in nerve terminals. Isoform 1 is more enriched than isoform 2 in developing brain as well as non-neuronal cells. Isoform 2 is very abundant in nerve terminals. |
Top Pathways | Inositol phosphate metabolism, Phosphatidylinositol signaling system |
Synaptojanin 1 CRISPR/Cas9 KO Plasmid (h) - sc-404077 from Santa Cruz Biotechnology
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Synaptojanin 1 HDR Plasmid (h) - sc-404077-HDR from Santa Cruz Biotechnology
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Synaptojanin 1 Double Nickase Plasmid (h) - sc-404077-NIC from Santa Cruz Biotechnology
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Synaptojanin 1 Double Nickase Plasmid (h2) - sc-404077-NIC-2 from Santa Cruz Biotechnology
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Synaptojanin 1 CRISPR Activation Plasmid (h) - sc-404077-ACT from Santa Cruz Biotechnology
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Synaptojanin 1 CRISPR Activation Plasmid (h2) - sc-404077-ACT-2 from Santa Cruz Biotechnology
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Synaptojanin 1 Lentiviral Activation Particles (h) - sc-404077-LAC from Santa Cruz Biotechnology
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Synaptojanin 1 Lentiviral Activation Particles (h2) - sc-404077-LAC-2 from Santa Cruz Biotechnology
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Synaptojanin 1 siRNA (h) - sc-39079 from Santa Cruz Biotechnology
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Synaptojanin 1 shRNA Plasmid (h) - sc-39079-SH from Santa Cruz Biotechnology
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Synaptojanin 1 shRNA (h) Lentiviral Particles - sc-39079-V from Santa Cruz Biotechnology
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Synaptojanin 1 RNAi - H00008867-R03 from Novus Biologicals
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Synaptojanin 1 RNAi - H00008867-R04 from Novus Biologicals
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MISSION® Human Phosphatase - SIHP1119 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP1120 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0882 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0880 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0881 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20898 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20898 from Sigma-Aldrich
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SYNJ1 siRNA (Human) - CRH5856 from Cohesion Biosciences
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SYNJ1 - MBS8227651 from MyBioSource
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shRNA set against Human SYNJ1 (NM_003895.3) - SHH421756 from Creative biogene
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Human SYNJ1 siRNA - orb266358 from Biorbyt
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SYNJ1 shRNA Plasmid (Human) - CHH5856 from Cohesion Biosciences
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