Gene Symbol | FANCA |
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Entrez Gene | 2175 |
Alt Symbol | FA, FA-H, FA1, FAA, FACA, FAH, FANCH |
Species | Human |
Gene Type | protein-coding |
Description | Fanconi anemia, complementation group A |
Other Description | Fanconi anemia group A protein|Fanconi anemia, complementation group H|Fanconi anemia, type 1 |
Swissprots | Q9Y6M2 Q9UEL9 Q9UPK3 B4DRI7 O15360 Q6PL10 Q92497 O75266 Q9UEL8 H3BSR5 A5D923 Q9UEA5 Q96H18 |
Accessions | AAC28331 AAC28751 AAC33304 AAC33401 AAS99350 CAA12393 CAA12394 CAB05445 CAB46098 CAB46099 CAB46100 CCQ42968 EAW66685 EAW66686 O15360 AK299282 BAG61299 AK301168 BAH13420 AY339878 AY339879 AY339880 BC008979 AAH08979 BC022498 BC064540 AAH64540 BC120978 AAI20979 BC120979 AAI20980 BC127633 AAI27634 BC141971 AAI41972 BC141972 AAI41973 BC156522 AAI56523 BC172515 AAI72515 BT007366 AAP36030 DQ574346 X99226 CAA67610 XM_005256294 XP_005256351 XM_011522945 XP_011521247 XM_011522946 XP_011521248 XM_011522947 XP_011521249 XM_011522948 XP_011521250 XR_933244 XR_933245 XR_933246 XR_933247 NM_000135 NP_000126 NM_001018112 NP_001018122 NM_001286167 NP_001273096 |
Function | DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. |
Subcellular Location | Nucleus. Cytoplasm. Note=The major form is nuclear. The minor form is cytoplasmic. |
Top Pathways | Fanconi anemia pathway |
FANCA CRISPR/Cas9 KO Plasmid (h) - sc-403205 from Santa Cruz Biotechnology
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FANCA HDR Plasmid (h) - sc-403205-HDR from Santa Cruz Biotechnology
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FANCA Double Nickase Plasmid (h) - sc-403205-NIC from Santa Cruz Biotechnology
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FANCA Double Nickase Plasmid (h2) - sc-403205-NIC-2 from Santa Cruz Biotechnology
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FANCA CRISPR Activation Plasmid (h) - sc-403205-ACT from Santa Cruz Biotechnology
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FANCA CRISPR Activation Plasmid (h2) - sc-403205-ACT-2 from Santa Cruz Biotechnology
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FANCA Lentiviral Activation Particles (h) - sc-403205-LAC from Santa Cruz Biotechnology
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FANCA Lentiviral Activation Particles (h2) - sc-403205-LAC-2 from Santa Cruz Biotechnology
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FANCA siRNA (h) - sc-40567 from Santa Cruz Biotechnology
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FANCA shRNA Plasmid (h) - sc-40567-SH from Santa Cruz Biotechnology
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FANCA shRNA (h) Lentiviral Particles - sc-40567-V from Santa Cruz Biotechnology
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Fumarylacetoacetate hydrolase RNAi - H00002184-R01 from Novus Biologicals
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FACA/FANCA RNAi - H00002175-R01 from Novus Biologicals
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FACA/FANCA RNAi - H00002175-R02 from Novus Biologicals
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MISSION® esiRNA - EHU064381 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1635 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1635 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07583 from Sigma-Aldrich
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FANCA siRNA (Human) - CRH1514 from Cohesion Biosciences
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FANCA - MBS8236366 from MyBioSource
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FANCA HDR Plasmid (h2) - sc-403205-HDR-2 from Santa Cruz Biotechnology
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FANCA CRISPR/Cas9 KO Plasmid (h2) - sc-403205-KO-2 from Santa Cruz Biotechnology
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shRNA set against Human FANCA (NM_000135.2) - SHH292253 from Creative biogene
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shRNA set against Human FANCA(NM_001018112.1) - SHH048755 from Creative biogene
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FANCA shRNA Plasmid (Human) - CHH1514 from Cohesion Biosciences
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