Gene Symbol | Artn |
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Entrez Gene | 11876 |
Alt Symbol | neublastin |
Species | Mouse |
Gene Type | protein-coding |
Description | artemin |
Other Description | - |
Swissprots | Q3SXF4 Q9Z0L2 Q3SXF5 |
Accessions | CAT02153 EDL30523 EDL30524 Q9Z0L2 AF109402 AAC98691 AK015393 BAB29827 AK053914 BAC35590 AK145190 AK156507 BAE33737 AK166013 BC104328 AAI04329 BC104329 AAI04330 BC140274 AAI40275 BC146573 AAI46574 XM_006502688 XP_006502751 XM_006502689 XP_006502752 XM_006502690 XP_006502753 XM_006502691 XP_006502754 XM_006502692 XP_006502755 XM_006502693 XP_006502756 XM_006502694 XP_006502757 XM_011240419 XP_011238721 NM_001284191 NP_001271120 NM_001284192 NP_001271121 NM_001284193 NP_001271122 NM_009711 NP_033841 |
Function | Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain (By similarity). Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch- like structures, a major component of the gut-associated lymphoid tissue. {ECO:0000250, ECO:0000269|PubMed:17322904}. |
Subcellular Location | Secreted {ECO:0000250}. |
Artn CRISPR/Cas9 KO Plasmid (m) - sc-419211 from Santa Cruz Biotechnology
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Artn HDR Plasmid (m) - sc-419211-HDR from Santa Cruz Biotechnology
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Artn Double Nickase Plasmid (m) - sc-419211-NIC from Santa Cruz Biotechnology
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Artn Double Nickase Plasmid (m2) - sc-419211-NIC-2 from Santa Cruz Biotechnology
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Artn CRISPR Activation Plasmid (m) - sc-419211-ACT from Santa Cruz Biotechnology
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Artn CRISPR Activation Plasmid (m2) - sc-419211-ACT-2 from Santa Cruz Biotechnology
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Artn Lentiviral Activation Particles (m) - sc-419211-LAC from Santa Cruz Biotechnology
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Artn Lentiviral Activation Particles (m2) - sc-419211-LAC-2 from Santa Cruz Biotechnology
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Artn siRNA (m) - sc-41967 from Santa Cruz Biotechnology
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Artn shRNA Plasmid (m) - sc-41967-SH from Santa Cruz Biotechnology
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Artn shRNA (m) Lentiviral Particles - sc-41967-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN27059 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND27059 from Sigma-Aldrich
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ARTN siRNA (Mouse) - CRM0268 from Cohesion Biosciences
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ARTN - MBS8233336 from MyBioSource
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shRNA set against Mouse ARTN (NM_009711.3) - SHH240994 from Creative biogene
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shRNA set against Mouse Artn(NM_009711.3) - SHG075589 from Creative biogene
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Mouse ARTN siRNA - orb279744 from Biorbyt
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ARTN shRNA Plasmid (Mouse) - CHM0268 from Cohesion Biosciences
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ARTN miRNA 3'UTR clone - MiUTR1M-01718 from Creative biogene
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