Gene Symbol |
Ang2
|
Entrez Gene |
11731
|
Alt Symbol |
Angrp, Raa3, Rnase5b
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
angiogenin, ribonuclease A family, member 2
|
Other Description |
angiogenin related protein|angiogenin-2|angiogenin-related protein|ribonuclease A a3
|
Swissprots |
Q64438 G5E8D0
|
Accessions |
AAA91367 CDG32016 EDL20851 Q64438 BC140357 AAI40358 BC146501 AAI46502 NM_007449 NP_031475
|
Function |
Has ribonuclease activity (in vitro). Seems to lack angiogenic activity. {ECO:0000269|PubMed:8633065}.
|
Subcellular Location |
Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000250}. Nucleus, nucleolus {ECO:0000250}. Note=Rapidly endocytosed by target cells and translocated to the nucleus where it accumulates in the nucleolus and binds to DNA. {ECO:0000250}.
|
Tissue Specificity |
Expressed (at protein level) in macrophages. {ECO:0000269|PubMed:16045902}.
|