FMR1

Gene Symbol	FMR1
Entrez Gene	2332
Alt Symbol	FMRP, FRAXA, POF, POF1
Species	Human
Gene Type	protein-coding
Description	fragile X mental retardation 1
Other Description	fragile X mental retardation protein 1
Swissprots	G8JL90 D3DWT0 D3DWT2 Q5PQZ6 A6NNH4 Q16578 Q99054 Q06787 D3DWT1
Accessions	AAA62452 AAA62453 AAA62454 AAA62455 AAA62456 AAA62457 AAA62458 AAA62459 AAA62460 AAA62461 AAA62462 AAA62463 AAA62464 AAA62465 AAA62466 AAA62467 AAA62468 AAA62469 AAB18828 AAB18829 AAB18830 AAB18831 AAB18832 AAB18833 AAD14228 EAW61293 EAW61294 EAW61295 EAW61296 EAW61297 EAW61298 EAW61299 EAW61300 EAW61301 EAW61302 EAW61303 Q06787 AB209188 BAD92425 AK294104 BAG57439 AK302707 BAG63929 BC038998 AAH38998 BC086957 AAH86957 BQ213316 BQ287827 BQ417290 BX498094 CK825936 CN315330 CX871385 KC774027 AGO02164 KC774028 AGO02165 KC774029 AGO02166 KF856234 AHI43787 KJ534836 AHW56476 KJ534837 AHW56477 KJ534838 AHW56478 M67468 AAA52458 S65791 AAB28395 X69962 CAA49586 NM_001185075 NP_001172004 NM_001185076 NP_001172005 NM_001185081 NP_001172010 NM_001185082 NP_001172011 NM_002024 NP_002015 NR_033699 NR_033700
Function	Translation repressor. Component of the CYFIP1-EIF4E- FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA- binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C). {ECO:0000250}.
Subcellular Location	Cytoplasm. Nucleus, nucleolus.
Tissue Specificity	Highest levels found in neurons, brain, testis, placenta and lymphocytes. Also expressed in epithelial tissues and at very low levels in glial cells. {ECO:0000269|PubMed:8401578, ECO:0000269|PubMed:8504300}.
Top Pathways	RNA transport

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FMR1 / FMRP ELISA Kit (Sandwich ELISA) - LS-F9020 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.313 ng/ml Range 0.313-20 ng/ml

Human FMR1 ELISA Kit - abx151571 from Abbexa Category ELISA Kit Sensitivity 0.105 ng/ml Range 0.313 ng/ml - 20 ng/ml

Fragile X Mental Retardation 1 (FMR1), Human, ELISA Kit - SEJ095Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.105ng/mL Range 0.312-20ng/mL

Fragile X mental retardation 1 protein (FMR1), Human, ELISA Kit - CSB-EL008756HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 3.9 pg/ml Range 15.6 pg/ml-1000 pg/ml

Fragile X Mental Retardation 1, ELISA Kit - MBS102927 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fragile X Mental Retardation 1, ELISA Kit - MBS095288 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fragile X Mental Retardation 1, ELISA Kit - MBS055865 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

fragile X mental retardation 1, ELISA Kit - MBS931448 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human FMR1 is typically less than 3.9 pg/ml.The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 15.6 pg/ml -1000 pg/ml.

Fragile X Mental Retardation 1, ELISA Kit - MBS053122 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1ng/ml Range 0.625ng/ml-20ng/ml

Fragile X Mental Retardation 1, ELISA Kit - MBS101290 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fragile X Mental Retardation 1, ELISA Kit - MBS072656 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fragile X Mental Retardation 1, ELISA Kit - MBS061681 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Fragile X Mental Retardation 1 (FMR1), ELISA Kit - MBS2020179 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.118ng/mL. Range 0.313-20ng/mL

ELISA Kit for Fragile X Mental Retardation 1 (FMR1) - SEJ095Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.118ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

CpG WIZ® Fragile X Amplification Kit - S7807 from EMD Millipore

Human Fragile X mental retardation 1 protein(FMR1) ELISA kit - CSB-EL008756HU from Cusabio Category ELISA Kit Sensitivity 3.9 pg/ml. Range 15.6 pg/ml-1000 pg/ml

ELISA Kit for Fragile X Mental Retardation 1 (FMR1) - SEJ095Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.118ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human Fragile X Mental Retardation 1 (FMR1) ELISA Kit - EKU04269 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.113 ng/mL Range 0.312-20 ng/mL

Fragile X Mental Retardation 1 (FMR1), Human, ELISA Kit - DL-FMR1-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.312-20 ng/mL

Human FMR1 ELISA Kit - abx573033 from Abbexa Category ELISA Kit Sensitivity 0.105 ng/ml Range 0.313 ng/ml - 20 ng/ml

Human Fragile X mental retardation 1 protein (FMR1) ELISA Kit - EKC33753 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,288.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 3.9 pg/ml Range 15.6 pg/ml-1000 pg/ml

Human FMR1 ELISA Kit - E015493 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of human FMR1 is typically less than 3.9 pg/ml.The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean

Human FMRP ELISA Kit - E015497 from Biobool Category ELISA Kit Sensitivity 1.0ng/ml.

FMR1 ELISA Kit (Human) (OKCD01047) - OKCD01047 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.113 ng/mL Range 0.312-20 ng/mL

anti-FMRP antibody - ARG64933 from Arigo Biolaboratories Category ELISA Kit

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