Gene Symbol | SERPINB2 |
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Entrez Gene | 5055 |
Alt Symbol | HsT1201, PAI, PAI-2, PAI2, PLANH2 |
Species | Human |
Gene Type | protein-coding |
Description | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
Other Description | monocyte Arg-serpin|placental plasminogen activator inhibitor|plasminogen activator inhibitor 2|plasminogen activator inhibitor, type II (arginine-serpin)|serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2|serpin B2|urokinase inhibitor |
Swissprots | Q96E96 P05120 |
Accessions | AAA36797 AAA60005 AAA60348 EAW63160 EAW63161 P05120 A21238 CAA01535 A21254 CAA01539 A32415 CAA02099 AK313159 BAG35977 BC012609 AAH12609 CD366374 DA543366 DQ656059 DQ892867 ABM83793 DQ896116 ABM87115 J02685 AAA36413 J03603 AAA60004 M18082 AAA60006 Y00630 CAA68666 NM_001143818 NP_001137290 NM_002575 NP_002566 |
Function | Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell- derived PAI-1. |
Subcellular Location | Cytoplasm. Secreted, extracellular space. |
Top Pathways | Amoebiasis |
PAI-2 CRISPR/Cas9 KO Plasmid (h) - sc-402054 from Santa Cruz Biotechnology
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PAI-2 HDR Plasmid (h) - sc-402054-HDR from Santa Cruz Biotechnology
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PAI-2 Double Nickase Plasmid (h) - sc-402054-NIC from Santa Cruz Biotechnology
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PAI-2 Double Nickase Plasmid (h2) - sc-402054-NIC-2 from Santa Cruz Biotechnology
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PAI-2 CRISPR Activation Plasmid (h) - sc-402054-ACT from Santa Cruz Biotechnology
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PAI-2 CRISPR Activation Plasmid (h2) - sc-402054-ACT-2 from Santa Cruz Biotechnology
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PAI-2 Lentiviral Activation Particles (h) - sc-402054-LAC from Santa Cruz Biotechnology
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PAI-2 Lentiviral Activation Particles (h2) - sc-402054-LAC-2 from Santa Cruz Biotechnology
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PAI-2 siRNA (h) - sc-40804 from Santa Cruz Biotechnology
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PAI-2 shRNA Plasmid (h) - sc-40804-SH from Santa Cruz Biotechnology
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PAI-2 shRNA (h) Lentiviral Particles - sc-40804-V from Santa Cruz Biotechnology
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SerpinB2 RNAi - H00005055-R01 from Novus Biologicals
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MISSION® esiRNA - EHU002791 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19142 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19142 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04210 from Sigma-Aldrich
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SERPINB2 siRNA (Human) - CRH3361 from Cohesion Biosciences
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SERPINB2 - MBS8203463 from MyBioSource
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shRNA set against Human SERPINB2 (NM_002575.2) - SHH405164 from Creative biogene
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Human SERPINB2 siRNA - orb263863 from Biorbyt
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SERPINB2 shRNA Plasmid (Human) - CHH3361 from Cohesion Biosciences
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SERPINB2 miRNA 3'UTR clone - MiUTR3H-01772 from Creative biogene
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SERPINB2 miRNA 3'UTR clone - MiUTR3H-01773 from Creative biogene
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