BCKDHB

Gene Symbol BCKDHB
Entrez Gene 594
Alt Symbol E1B, dJ279A18.1
Species Human
Gene Type protein-coding
Description branched chain keto acid dehydrogenase E1, beta polypeptide
Other Description 2-oxoisovalerate dehydrogenase beta subunit|2-oxoisovalerate dehydrogenase subunit beta, mitochondrial|BCKDE1B|BCKDH E1-beta|E1b-beta subunit of the branched-chain complex|branched chain alpha-ketoacid dehydrogenase E1-beta subunit|branched-chain alpha-keto acid dehydrogenase E1 component beta chain
Swissprots P21953 Q5T2J3 Q9BQL0
Accessions AAB09779 BAA14389 EAW48696 EAW48697 EAW48698 P21953 AK289977 BAF82666 AK304353 BAG65195 AK310838 AK316545 BAH14916 BC034481 AAH34481 BC040139 AAH40139 BM553932 BT020063 AAV38866 DB548202 DC372349 M55575 AAA51812 U50708 AAB16763 U51016 AAB09780 X52446 CAA36685 XM_005248756 XP_005248813 XM_006715542 XP_006715605 XM_011536023 XP_011534325 XM_011536024 XP_011534326 XM_011536025 XP_011534327 XM_011536026 XP_011534328 XM_011536027 XP_011534329 NM_000056 NP_000047 NM_183050 NP_898871
Function The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
Subcellular Location Mitochondrion matrix.
Top Pathways Valine, leucine and isoleucine degradation

BCKDHB CRISPR/Cas9 KO Plasmid (h) - sc-406787 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BCKDHB HDR Plasmid (h) - sc-406787-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BCKDHB Double Nickase Plasmid (h) - sc-406787-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BCKDHB Double Nickase Plasmid (h2) - sc-406787-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BCKDHB CRISPR Activation Plasmid (h) - sc-406787-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BCKDHB CRISPR Activation Plasmid (h2) - sc-406787-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BCKDHB Lentiviral Activation Particles (h) - sc-406787-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BCKDHB Lentiviral Activation Particles (h2) - sc-406787-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BCKDHB siRNA (h) - sc-95231 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BCKDHB shRNA Plasmid (h) - sc-95231-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BCKDHB shRNA (h) Lentiviral Particles - sc-95231-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU064131 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3902 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3902 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

BCKDHB siRNA (Human) - CRH0407 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BCKDHB - MBS8211212 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human BCKDHB (NM_183050.2) - SHH245822 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human BCKDHB(NM_000056.3) - SHG096685 from Creative biogene

Category siRNA
Species Reactivities Human

Human BCKDHB siRNA - orb260909 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BCKDHB shRNA Plasmid (Human) - CHH0407 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

BCKDHB miRNA 3'UTR clone - MiUTR3H-02477 from Creative biogene

Species Reactivities Human
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