Gene Symbol | GSTA4 |
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Entrez Gene | 2941 |
Alt Symbol | GSTA4-4, GTA4 |
Species | Human |
Gene Type | protein-coding |
Description | glutathione S-transferase alpha 4 |
Other Description | GST class-alpha member 4|S-(hydroxyalkyl)glutathione lyase A4|glutathione S-alkyltransferase A4|glutathione S-aralkyltransferase A4|glutathione S-aryltransferase A4|glutathione S-transferase A4|glutathione S-transferase A4-4|glutathione transferase A4-4 |
Swissprots | Q9H414 O15217 Q9BX18 Q6P4G1 B2RD15 Q5T7Q8 |
Accessions | AAC72706 AAW56075 EAX04393 EAX04394 EAX04395 EAX04396 EAX04397 EAX04398 EAX04399 O15217 AA709059 AF020918 AAD04711 AF025887 AAC39695 AF125271 AAD27704 AF125272 AAD27705 AF125273 AAD27706 AK054804 BAG51425 AK315369 BAG37762 BC015523 AAH15523 BC063439 AAH63439 BC096817 BG716171 CR749474 CAH18304 DA521337 DQ890661 ABM81587 DQ893841 ABM84767 Y13047 CAA73482 XM_005249035 XP_005249092 XM_011514534 XP_011512836 XM_011514535 XP_011512837 NM_001512 NP_001503 |
Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. This isozyme has a high catalytic efficiency with 4-hydroxyalkenals such as 4- hydroxynonenal (4-HNE). {ECO:0000269|PubMed:10329152, ECO:0000269|PubMed:20085333}. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Expressed at a high level in brain, placenta, and skeletal muscle and much lower in lung and liver. |
Top Pathways | Chemical carcinogenesis, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450 |
Human GSTA4 full length protein - ab117039 from Abcam
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Human GSTA4 full length protein - ab124583 from Abcam
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Human GSTA4 protein fragment - ab117040 from Abcam
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GSTA4 Antibody Blocking Peptide - LS-E9879 from LifeSpan Bioscience
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GSTA4 Antibody Blocking Peptide - LS-E17564 from LifeSpan Bioscience
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GSTA4 Antibody Blocking Peptide - LS-E17565 from LifeSpan Bioscience
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GSTA4 Partial Recombinant Protein - H00002941-Q01 from Novus Biologicals
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GSTA4 Recombinant Protein - H00002941-P01 from Novus Biologicals
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Recombinant Human GSTA4 Protein - NBP1-99022 from Novus Biologicals
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GSTA4-Antibody-N-term-Blocking-Peptide - BP8970a from Abgent, a WuXi AppTec company
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Human GSTA4 protein - orb168451 from Biorbyt
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GSTA4 Blocking Peptide - 33R-5405 from Fitzgerald
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GSTA4 protein (His tag) - 80R-2245 from Fitzgerald
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Human GSTa4 Protein - abx066838 from Abbexa
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GSTA4 (1-222, His-tag) - AR50328PU-N from Acris Antibodies
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GSTA4 (1-222, His-tag) - AR50328PU-S from Acris Antibodies
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GSTA4 - H00002941-P01-02 from Acris Antibodies
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GSTA4 - H00002941-Q01-10 from Acris Antibodies
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GSTA4 - H00002941-Q01-25 from Acris Antibodies
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Glutathione S Transferase Alpha 4 (GSTa4), Human - 20-6953 from ARP American Research Products
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GSTA4, 1-222aa, Human, His tag, E.coli - 01-P1504 from ARP American Research Products
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GSTA4 fusion protein - Ag11206 from Proteintech Group
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GSTA4 fusion protein - Ag11028 from Proteintech Group
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GSTA4 Human - ENPS-607 from NeoScientific
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Recombinant Human Glutathione S-Transferase Alpha 4 Enzyme - BP002797-ENZ-600 from Syd Labs
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