| Gene Symbol |
Ppt1
|
| Entrez Gene |
19063
|
| Alt Symbol |
9530043G02Rik, AA960502, C77813, CLN1, D4Ertd184e, INCL, PPT
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
palmitoyl-protein thioesterase 1
|
| Other Description |
PPT-1|palmitoyl-protein hydrolase 1
|
| Swissprots |
Q9D681 O88531 Q9WTY3
|
| Accessions |
EDL30401 O88531 AF071025 AAC25398 AF087568 AAD25224 AF326557 AAL37403 AF326558 AAL37404 AK014561 AK018046 AK079228 AK148314 BAE28475 AK151055 BAE30072 AK151107 BAE30117 AK152474 BAE31248 AK152940 BAE31611 AK153106 BAE31725 AK153316 AK169579 BAE41238 AK169658 AK171668 BAE42600 AK192077 AK192572 AK195785 AK207374 AK216167 BC099945 BC141455 AAI41456 BC148714 AAI48715 CB600397 XR_376299 NM_008917 NP_032943
|
| Function |
Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons.
|
| Subcellular Location |
Lysosome.
|
| Tissue Specificity |
Highest level in testis and kidney, lower in heart, brain and lung and lowest in skeletal muscle.
|
| Top Pathways |
Lysosome, Fatty acid elongation, Fatty acid metabolism
|