Gene Symbol | SYCE2 |
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Entrez Gene | 256126 |
Alt Symbol | CESC1 |
Species | Human |
Gene Type | protein-coding |
Description | synaptonemal complex central element protein 2 |
Other Description | - |
Swissprots | Q6PIF2 B4DYD3 |
Accessions | Q6PIF2 AK097443 AK302373 BAG63695 BC035819 AAH35819 BC172302 AAI72302 DB449708 XM_005259848 XP_005259905 XM_011527882 XP_011526184 XM_011527883 XP_011526185 NM_001105578 NP_001099048 |
Function | Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Requires SYCP1 in order to be incorporated into the central element. May have a role in the synaptonemal complex assembly, stabilization and recombination (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus. Note=Associates with chromatin. In prophase I stage of meiosis, localizes in the transverse central elements of the central region between lateral elements of the synaptonemal complexes. Found only where the chromosome cores are synapsed. Colocalizes with SYCE1 in the central elements (By similarity). {ECO:0000250}. |
SYCE2 CRISPR/Cas9 KO Plasmid (h) - sc-409079 from Santa Cruz Biotechnology
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SYCE2 HDR Plasmid (h) - sc-409079-HDR from Santa Cruz Biotechnology
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SYCE2 Double Nickase Plasmid (h) - sc-409079-NIC from Santa Cruz Biotechnology
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SYCE2 Double Nickase Plasmid (h2) - sc-409079-NIC-2 from Santa Cruz Biotechnology
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SYCE2 CRISPR Activation Plasmid (h) - sc-409079-ACT from Santa Cruz Biotechnology
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SYCE2 CRISPR Activation Plasmid (h2) - sc-409079-ACT-2 from Santa Cruz Biotechnology
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SYCE2 Lentiviral Activation Particles (h) - sc-409079-LAC from Santa Cruz Biotechnology
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SYCE2 Lentiviral Activation Particles (h2) - sc-409079-LAC-2 from Santa Cruz Biotechnology
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SYCE2 siRNA (h) - sc-106961 from Santa Cruz Biotechnology
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SYCE2 shRNA Plasmid (h) - sc-106961-SH from Santa Cruz Biotechnology
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SYCE2 shRNA (h) Lentiviral Particles - sc-106961-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU129961 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20875 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20875 from Sigma-Aldrich
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SYCE2 siRNA (Human) - CRJ6743 from Cohesion Biosciences
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SYCE2 - MBS8237780 from MyBioSource
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shRNA set against Human Syce2 (NM_001105578.1) - SHH421476 from Creative biogene
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SYCE2 shRNA Plasmid (Human) - CHJ6743 from Cohesion Biosciences
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