Gene Symbol | ECHS1 |
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Entrez Gene | 1892 |
Alt Symbol | ECHS1D, SCEH |
Species | Human |
Gene Type | protein-coding |
Description | enoyl CoA hydratase, short chain, 1, mitochondrial |
Other Description | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial|enoyl-CoA hydratase, mitochondrial |
Swissprots | Q5VWY1 O00739 Q96H54 P30084 |
Accessions | CAA66808 EAW61339 P30084 BC008906 AAH08906 BC013264 BE906357 BI091611 BQ130816 BT007123 AAP35787 D13900 BAA03001 NM_004092 NP_004083 |
Function | Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate. |
Subcellular Location | Mitochondrion matrix. |
Tissue Specificity | Liver, fibroblast, muscle. Barely detectable in spleen and kidney. |
Top Pathways | Tryptophan metabolism, Fatty acid degradation, Fatty acid elongation, Carbon metabolism, Lysine degradation |
ECHS1 CRISPR/Cas9 KO Plasmid (h) - sc-406053 from Santa Cruz Biotechnology
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ECHS1 HDR Plasmid (h) - sc-406053-HDR from Santa Cruz Biotechnology
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ECHS1 Double Nickase Plasmid (h) - sc-406053-NIC from Santa Cruz Biotechnology
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ECHS1 Double Nickase Plasmid (h2) - sc-406053-NIC-2 from Santa Cruz Biotechnology
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ECHS1 CRISPR Activation Plasmid (h) - sc-406053-ACT from Santa Cruz Biotechnology
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ECHS1 CRISPR Activation Plasmid (h2) - sc-406053-ACT-2 from Santa Cruz Biotechnology
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ECHS1 Lentiviral Activation Particles (h) - sc-406053-LAC from Santa Cruz Biotechnology
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ECHS1 Lentiviral Activation Particles (h2) - sc-406053-LAC-2 from Santa Cruz Biotechnology
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ECHS1 siRNA (h) - sc-90799 from Santa Cruz Biotechnology
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ECHS1 shRNA Plasmid (h) - sc-90799-SH from Santa Cruz Biotechnology
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ECHS1 shRNA (h) Lentiviral Particles - sc-90799-V from Santa Cruz Biotechnology
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ECHS1 RNAi - H00001892-R01 from Novus Biologicals
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MISSION® esiRNA - EHU013841 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7635 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7635 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03002 from Sigma-Aldrich
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ECHS1 siRNA (Human) - CRH1318 from Cohesion Biosciences
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ECHS1 - MBS8230914 from MyBioSource
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ECHS1 CRISPR/Cas9 KO Plasmid (h2) - sc-406053-KO-2 from Santa Cruz Biotechnology
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ECHS1 HDR Plasmid (h2) - sc-406053-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human ECHS1 (NM_004092.3) - SHH282929 from Creative biogene
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Human ECHS1 siRNA - orb261820 from Biorbyt
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ECHS1 shRNA Plasmid (Human) - CHH1318 from Cohesion Biosciences
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ECHS1 miRNA 3'UTR clone - MiUTR3H-04849 from Creative biogene
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