GALE

Gene Symbol GALE
Entrez Gene 2582
Alt Symbol SDR1E1
Species Human
Gene Type protein-coding
Description UDP-galactose-4-epimerase
Other Description UDP galactose-4'-epimerase|UDP-GalNAc 4-epimerase|UDP-GlcNAc 4-epimerase|UDP-N-acetylgalactosamine 4-epimerase|UDP-N-acetylglucosamine 4-epimerase|UDP-galactose 4-epimerase|UDP-glucose 4-epimerase|galactose-4-epimerase, UDP-|galactowaldenase|short chain dehydrogenase/reductase family 1E, member 1
Swissprots Q86W41 Q14376 Q9UJB4 A0A024RAH5 Q9BVE3 Q38G75 B3KQ39
Accessions AAC39645 ABB04109 CBX87741 EAW95083 EAW95084 EAW95085 EAW95086 EAW95087 EAW95088 EAW95089 EAW95090 EAW95091 EAW95092 EAW95093 Q14376 AK057302 BAG51901 AK096127 AK307354 AK314397 BAG37021 AL530475 BC001273 AAH01273 BC050685 AAH50685 BC056880 BI835132 BQ437612 DA043957 DQ233668 ABB04110 DQ891753 ABM82679 DQ894934 ABM85860 L41668 AAB86498 NM_000403 NP_000394 NM_001008216 NP_001008217 NM_001127621 NP_001121093
Function Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6- phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP- GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids. {ECO:0000269|PubMed:22654673, ECO:0000303|PubMed:23732289}.
Top Pathways Amino sugar and nucleotide sugar metabolism, Galactose metabolism

GALE CRISPR/Cas9 KO Plasmid (h) - sc-408127 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GALE HDR Plasmid (h) - sc-408127-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GALE Double Nickase Plasmid (h) - sc-408127-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GALE Double Nickase Plasmid (h2) - sc-408127-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GALE CRISPR Activation Plasmid (h) - sc-408127-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GALE CRISPR Activation Plasmid (h2) - sc-408127-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GALE Lentiviral Activation Particles (h) - sc-408127-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GALE Lentiviral Activation Particles (h2) - sc-408127-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GALE siRNA (h) - sc-78950 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GALE shRNA Plasmid (h) - sc-78950-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GALE shRNA (h) Lentiviral Particles - sc-78950-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GALE RNAi - H00002582-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU044651 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1261 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1261 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02707 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02707

GALE siRNA (Human) - CRH1718 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GALE RNAi - H00002582-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

GALE - MBS8233551 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GALE (NM_000403.3) - SHH298885 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human GALE(NM_000403.3) - SHH075593 from Creative biogene

Category siRNA
Species Reactivities Human

Human GALE siRNA - orb262220 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GALE shRNA Plasmid (Human) - CHH1718 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GALE miRNA 3'UTR clone - MiUTR1H-03932 from Creative biogene

Species Reactivities Human
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