Gene Symbol | FANCG |
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Entrez Gene | 2189 |
Alt Symbol | FAG, XRCC9 |
Species | Human |
Gene Type | protein-coding |
Description | Fanconi anemia, complementation group G |
Other Description | DNA repair protein XRCC9|Fanconi anemia group G protein|X-ray repair complementing defective repair in Chinese hamster cells 9|X-ray repair, complementing defective, in Chinese hamster, 9 |
Swissprots | O15287 |
Accessions | AAC07981 AAV40841 EAW58401 EAW58402 O15287 AJ007669 CAA07602 AK293427 BAG56932 AK311348 AK312987 BAG35824 BC000032 AAH00032 BC011623 AAH11623 BT009813 AAP88815 DQ892166 ABM83092 DQ895360 ABM86286 U70310 AAB80802 NM_004629 NP_004620 |
Function | DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:18550849}. Cytoplasm {ECO:0000269|PubMed:18550849}. Note=The major form is nuclear. The minor form is cytoplasmic. |
Tissue Specificity | Highly expressed in testis and thymus. Found in lymphoblasts. |
Top Pathways | Fanconi anemia pathway |
FANCG CRISPR/Cas9 KO Plasmid (h) - sc-405314 from Santa Cruz Biotechnology
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FANCG HDR Plasmid (h) - sc-405314-HDR from Santa Cruz Biotechnology
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FANCG Double Nickase Plasmid (h) - sc-405314-NIC from Santa Cruz Biotechnology
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FANCG Double Nickase Plasmid (h2) - sc-405314-NIC-2 from Santa Cruz Biotechnology
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FANCG CRISPR Activation Plasmid (h) - sc-405314-ACT from Santa Cruz Biotechnology
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FANCG CRISPR Activation Plasmid (h2) - sc-405314-ACT-2 from Santa Cruz Biotechnology
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FANCG Lentiviral Activation Particles (h) - sc-405314-LAC from Santa Cruz Biotechnology
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FANCG Lentiviral Activation Particles (h2) - sc-405314-LAC-2 from Santa Cruz Biotechnology
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FANCG siRNA (h) - sc-92893 from Santa Cruz Biotechnology
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FANCG shRNA Plasmid (h) - sc-92893-SH from Santa Cruz Biotechnology
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FANCG shRNA (h) Lentiviral Particles - sc-92893-V from Santa Cruz Biotechnology
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FANCG RNAi - H00002189-R01V from Novus Biologicals
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FANCG RNAi - H00002189-R01 from Novus Biologicals
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MISSION® esiRNA - EHU218071 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1406 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1407 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1408 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1407 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1408 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1406 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12022 from Sigma-Aldrich
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FANCG siRNA (Human) - CRH1526 from Cohesion Biosciences
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FANCG - MBS8224241 from MyBioSource
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shRNA set against Human FANCG(NM_004629.1) - SHH049007 from Creative biogene
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Human FANCG siRNA - orb262028 from Biorbyt
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