Gene Symbol | ATP6V1E2 |
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Entrez Gene | 90423 |
Alt Symbol | ATP6E1, ATP6EL2, ATP6V1EL2, VMA4 |
Species | Human |
Gene Type | protein-coding |
Description | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2 |
Other Description | V-ATPase subunit E 2|V-type proton ATPase subunit E 2|vacuolar proton pump subunit E 2|vacuolar-type proton-translocating ATPase subunit E1 |
Swissprots | Q96A05 |
Accessions | AAY14833 EAX00253 Q96A05 AB074759 BAC00847 AK058055 BAB71643 BC008981 AAH08981 BC034808 AAH34808 BG717423 HQ447099 ADQ31586 XM_005264633 XP_005264690 XM_005264634 XP_005264691 XM_011533148 XP_011531450 XM_011533149 XP_011531451 XM_011533150 XP_011531452 XM_011533151 XP_011531453 XM_011533152 XP_011531454 XM_011533153 XP_011531455 XR_939738 XR_939739 NM_080653 NP_542384 |
Function | Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity). {ECO:0000250}. |
Tissue Specificity | Testis specific. {ECO:0000269|PubMed:12036578}. |
Top Pathways | Epithelial cell signaling in Helicobacter pylori infection, Vibrio cholerae infection, Collecting duct acid secretion, Phagosome, Rheumatoid arthritis |
ATP6E1 CRISPR/Cas9 KO Plasmid (h) - sc-418036 from Santa Cruz Biotechnology
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ATP6E1 HDR Plasmid (h) - sc-418036-HDR from Santa Cruz Biotechnology
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ATP6E1 Double Nickase Plasmid (h) - sc-418036-NIC from Santa Cruz Biotechnology
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ATP6E1 Double Nickase Plasmid (h2) - sc-418036-NIC-2 from Santa Cruz Biotechnology
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ATP6E1 CRISPR Activation Plasmid (h) - sc-418036-ACT from Santa Cruz Biotechnology
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ATP6E1 CRISPR Activation Plasmid (h2) - sc-418036-ACT-2 from Santa Cruz Biotechnology
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ATP6E1 Lentiviral Activation Particles (h) - sc-418036-LAC from Santa Cruz Biotechnology
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ATP6E1 Lentiviral Activation Particles (h2) - sc-418036-LAC-2 from Santa Cruz Biotechnology
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ATP6E1 siRNA (h) - sc-94859 from Santa Cruz Biotechnology
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ATP6E1 shRNA Plasmid (h) - sc-94859-SH from Santa Cruz Biotechnology
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ATP6E1 shRNA (h) Lentiviral Particles - sc-94859-V from Santa Cruz Biotechnology
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ATP6V1E2 RNAi - H00090423-R02 from Novus Biologicals
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MISSION® esiRNA - EHU047801 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3733 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3733 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01130 from Sigma-Aldrich
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ATP6V1E2 siRNA (Human) - CRJ3946 from Cohesion Biosciences
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ATP6V1E2 - MBS8227827 from MyBioSource
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shRNA set against Human ATP6V1E2 (NM_080653.3) - SHH243178 from Creative biogene
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shRNA set against Human ATP6V1E2(NM_080653.3) - SHG084097 from Creative biogene
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ATP6V1E2 shRNA Plasmid (Human) - CHJ3946 from Cohesion Biosciences
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ATP6V1E2 miRNA 3'UTR clone - MiUTR1H-00723 from Creative biogene
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