| Gene Symbol | ATP6V1E2 |
|---|---|
| Entrez Gene | 90423 |
| Alt Symbol | ATP6E1, ATP6EL2, ATP6V1EL2, VMA4 |
| Species | Human |
| Gene Type | protein-coding |
| Description | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2 |
| Other Description | V-ATPase subunit E 2|V-type proton ATPase subunit E 2|vacuolar proton pump subunit E 2|vacuolar-type proton-translocating ATPase subunit E1 |
| Swissprots | Q96A05 |
| Accessions | AAY14833 EAX00253 Q96A05 AB074759 BAC00847 AK058055 BAB71643 BC008981 AAH08981 BC034808 AAH34808 BG717423 HQ447099 ADQ31586 XM_005264633 XP_005264690 XM_005264634 XP_005264691 XM_011533148 XP_011531450 XM_011533149 XP_011531451 XM_011533150 XP_011531452 XM_011533151 XP_011531453 XM_011533152 XP_011531454 XM_011533153 XP_011531455 XR_939738 XR_939739 NM_080653 NP_542384 |
| Function | Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity). {ECO:0000250}. |
| Tissue Specificity | Testis specific. {ECO:0000269|PubMed:12036578}. |
| Top Pathways | Epithelial cell signaling in Helicobacter pylori infection, Vibrio cholerae infection, Collecting duct acid secretion, Phagosome, Rheumatoid arthritis |