Function |
General regulatory factor (GRF) that contributes to transcriptional activation of a large number of genes, as well as to DNA replication, silencing and telomere structure. Involved in the transcription activation of a subset of ribosomal protein genes. Binds the ARS-elements found in many promoters. Binds to the sequence 5'-TCN(7)ACG-3'. Influences on genome-wide nucleosome occupancy and affects chromatin structure, and probably dynamics. As a component of the global genome repair (GGR) complex, promotes global genome nucleotide excision repair (GG-NER) which removes DNA damage from nontranscribing DNA. Component of the regulatory network controlling mitotic and meiotic cell cycle progression. {ECO:0000269|PubMed:10601031, ECO:0000269|PubMed:10684934, ECO:0000269|PubMed:11713306, ECO:0000269|PubMed:11756546, ECO:0000269|PubMed:12200417, ECO:0000269|PubMed:15177043, ECO:0000269|PubMed:15456886, ECO:0000269|PubMed:16908533, ECO:0000269|PubMed:17158163, ECO:0000269|PubMed:18305101, ECO:00
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