ASMT

Gene Symbol ASMT
Entrez Gene 438
Alt Symbol ASMTY, HIOMT, HIOMTY
Species Human
Gene Type protein-coding
Description acetylserotonin O-methyltransferase
Other Description acetylserotonin N-methyltransferase|acetylserotonin methyltransferase (Y chromosome)|hydroxyindole O-methyltransferase
Swissprots B2RC33 Q5JQ73 Q16598 Q5JQ72 P46597
Accessions AAA75289 AAA75290 AAA75291 EAW98685 EAW98686 P46597 AK314922 BAG37430 BC001620 AAH01620 KJ534774 AHW56414 KJ534775 AHW56415 KJ534776 AHW56416 KJ535045 AHW56684 M83779 AAA17020 U11090 AAA58582 U11091 AAA58583 NM_001171038 NP_001164509 NM_001171039 NP_001164510 NM_004043 NP_004034
Function Isoform 1 catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5- methoxytryptamine). Isoform 2 and isoform 3 lack enzyme activity. {ECO:0000269|PubMed:22775292}.
Tissue Specificity Expressed in the pineal gland (at protein level). In the retina, very low expression is found at the mRNA level (PubMed:7989373), and not at the protein level (PubMed:8574683). {ECO:0000269|PubMed:22775292, ECO:0000269|PubMed:7989373, ECO:0000269|PubMed:8574683}.
Top Pathways Tryptophan metabolism

ASMT-Over-expression-Lysate - LY12289a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag ASMT (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ASMT gene

ASMT Overexpression Lysate (Native) - NBP2-07921 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: ASMT Overexpression Lysate (Adult Normal) [NBP2-07921] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ASMT.

Panoply™ Human ASMT Knockdown Stable Cell Line - CSC-DC001047 from Creative biogene

Category Cell Line
Species Human
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