C4BPB

Gene Symbol	C4BPB
Entrez Gene	725
Alt Symbol	C4BP
Species	Human
Gene Type	protein-coding
Description	complement component 4 binding protein, beta
Other Description	C4b-binding protein beta chain
Swissprots	Q9BS25 D3DT81 Q5VVR0 P20851 A5JYP8
Accessions	ABQ52216 EAW93504 EAW93505 EAW93506 P20851 AK092427 AK293379 BAG56891 AK315137 BC005378 AAH05378 BG568018 BM987840 H63461 JF432656 ADZ15873 L11245 AAA35616 M29964 AAB59520 XM_005273253 XP_005273310 XM_005273254 XP_005273311 XM_005273255 XP_005273312 NM_000716 NP_000707 NM_001017364 NP_001017364 NM_001017365 NP_001017365 NM_001017366 NP_001017366 NM_001017367 NP_001017367
Function	Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S.
Subcellular Location	Secreted.
Top Pathways	Complement and coagulation cascades, Pertussis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

C4BPβ siRNA (h) - sc-42741 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

C4BPβ shRNA Plasmid (h) - sc-42741-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

C4BPβ shRNA (h) Lentiviral Particles - sc-42741-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

C4 binding protein B RNAi - H00000725-R03 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

C4 binding protein B RNAi - H00000725-R04 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

C4 binding protein B RNAi - H00000725-R02 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

C4 binding protein B RNAi - H00000725-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

C4 binding protein B RNAi - H00000725-R05 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU052671 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN4931 from Sigma-Aldrich Category ZFN Kit

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4931 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

C4BPB siRNA (Human) - CRH0502 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

C4BPB - MBS8204771 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

C4BPB shRNA Plasmid (Human) - CHH0502 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

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