Gene Symbol | Il2 |
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Entrez Gene | 16183 |
Alt Symbol | Il-2 |
Species | Mouse |
Gene Type | protein-coding |
Description | interleukin 2 |
Other Description | T-cell growth factor|TCGF|interleukin-2 |
Swissprots | P97945 Q791T3 P04351 |
Accessions | AAA39281 AAA39326 AAA39328 AAF22747 AAF22748 AAF32272 AAK91717 CAA25823 CAA25824 CAA25825 EDL35098 P04351 AF065914 AAD25890 AF065915 AAD25891 AF065916 AAD25892 AF352786 AAK52904 AF538059 AAN77291 AF542383 AAN77288 AF542384 AAN77289 AF542385 AAN77290 AY147902 AAN38301 BC116845 AAI16846 BC116873 AAI16874 BX519775 DQ836354 ABH04319 K02292 AAA39289 U41494 AAB39206 U41504 AAB39208 U41505 AAB39209 U41506 AAB39210 X01772 CAA25909 X66058 CAA46854 X73040 NM_008366 NP_032392 |
Function | Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine- activated killer cells, natural killer cells, and glioma cells. |
Subcellular Location | Secreted. |
Top Pathways | Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Type I diabetes mellitus, Chagas disease (American trypanosomiasis), Graft-versus-host disease |
IL-2 CRISPR/Cas9 KO Plasmid (m) - sc-421104 from Santa Cruz Biotechnology
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IL-2 HDR Plasmid (m) - sc-421104-HDR from Santa Cruz Biotechnology
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IL-2 Double Nickase Plasmid (m) - sc-421104-NIC from Santa Cruz Biotechnology
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IL-2 Double Nickase Plasmid (m2) - sc-421104-NIC-2 from Santa Cruz Biotechnology
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IL-2 CRISPR Activation Plasmid (m) - sc-421104-ACT from Santa Cruz Biotechnology
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IL-2 CRISPR Activation Plasmid (m2) - sc-421104-ACT-2 from Santa Cruz Biotechnology
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IL-2 Lentiviral Activation Particles (m) - sc-421104-LAC from Santa Cruz Biotechnology
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IL-2 Lentiviral Activation Particles (m2) - sc-421104-LAC-2 from Santa Cruz Biotechnology
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IL-2 siRNA (m) - sc-39620 from Santa Cruz Biotechnology
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IL-2 shRNA Plasmid (m) - sc-39620-SH from Santa Cruz Biotechnology
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IL-2 shRNA (m) Lentiviral Particles - sc-39620-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN33773 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND33773 from Sigma-Aldrich
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IL2 siRNA (Mouse) - CRM2057 from Cohesion Biosciences
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IL2 - MBS8217728 from MyBioSource
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shRNA set against Mouse IL2 (NM_008366.3) - SHH318645 from Creative biogene
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Mouse IL2 siRNA - orb281533 from Biorbyt
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IL2 shRNA Plasmid (Mouse) - CHM2057 from Cohesion Biosciences
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