Gene Symbol | TRHDE |
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Entrez Gene | 29953 |
Alt Symbol | PAP-II, PGPEP2, TRH-DE |
Species | Human |
Gene Type | protein-coding |
Description | thyrotropin-releasing hormone degrading enzyme |
Other Description | TRH-degrading ectoenzyme|TRH-specific aminopeptidase|pyroglutamyl aminopeptidase II|pyroglutamyl-peptidase II|thyroliberinase|thyrotropin-releasing hormone degrading ectoenzyme|thyrotropin-releasing hormone-degrading ectoenzyme |
Swissprots | Q9UKU6 Q6UWJ4 A5PL19 |
Accessions | EAW97281 Q9UKU6 AF126372 AAF13141 AK026034 AY358765 AAQ89125 BC023230 BC142706 AAI42707 BC150181 AAI50182 XM_005268819 XP_005268876 XM_011538248 XP_011536550 XR_944529 NM_013381 NP_037513 |
Function | Specific inactivation of TRH after its release. |
Subcellular Location | Membrane; Single-pass type II membrane protein. |
Tissue Specificity | Predominantly expressed in brain. |
TRH-DE CRISPR/Cas9 KO Plasmid (h) - sc-412057 from Santa Cruz Biotechnology
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TRH-DE HDR Plasmid (h) - sc-412057-HDR from Santa Cruz Biotechnology
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TRH-DE Double Nickase Plasmid (h) - sc-412057-NIC from Santa Cruz Biotechnology
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TRH-DE Double Nickase Plasmid (h2) - sc-412057-NIC-2 from Santa Cruz Biotechnology
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TRH-DE CRISPR Activation Plasmid (h) - sc-412057-ACT from Santa Cruz Biotechnology
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TRH-DE CRISPR Activation Plasmid (h2) - sc-412057-ACT-2 from Santa Cruz Biotechnology
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TRH-DE Lentiviral Activation Particles (h) - sc-412057-LAC from Santa Cruz Biotechnology
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TRH-DE Lentiviral Activation Particles (h2) - sc-412057-LAC-2 from Santa Cruz Biotechnology
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TRH-DE siRNA (h) - sc-76728 from Santa Cruz Biotechnology
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TRH-DE shRNA Plasmid (h) - sc-76728-SH from Santa Cruz Biotechnology
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TRH-DE shRNA (h) Lentiviral Particles - sc-76728-V from Santa Cruz Biotechnology
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TRH-degrading Ectoenzyme/TRHDE RNAi - H00029953-R01 from Novus Biologicals
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MISSION® esiRNA - EHU014551 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21948 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21948 from Sigma-Aldrich
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TRHDE siRNA (Human) - CRH9295 from Cohesion Biosciences
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TRHDE - MBS8218736 from MyBioSource
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shRNA set against Human Trhde (NM_013381.2) - SHH434272 from Creative biogene
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Human TRHDE siRNA - orb269797 from Biorbyt
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TRHDE shRNA Plasmid (Human) - CHH9295 from Cohesion Biosciences
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TRHDE miRNA 3'UTR clone - MiUTR4H-TG09330 from Creative biogene
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